Results 31 to 40 of about 7,284 (241)

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

eLife, 2017
Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] is essential for exocytosis. Classical ways of manipulating PI(4,5)P2 levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P2 from those of its metabolites.
Alexander M Walter, Rainer Müller, Bassam Tawfik, Keimpe DB Wierda, Paulo S Pinheiro, André Nadler, Anthony W McCarthy, Iwona Ziomkiewicz, Martin Kruse, Gregor Reither, Jens Rettig, Martin Lehmann, Volker Haucke, Bertil Hille, Carsten Schultz, Jakob Balslev Sørensen   +15 more
doaj   +1 more source

Secretory activity and endocrine regulation of male accessory glands in the blood-sucking bug Panstrongylus megistus (Hemiptera: Reduviidae)

Memorias do Instituto Oswaldo Cruz, 1987
The epithelial cells of Panstrongylus megistus male accessory glands (MAG) present ultrastructural characteristics of a secretory cell. Their secretory products are accumulated in the lumen of the four MAG lobes.
Lêda Regis, André F. Furtado, Yara de M. Gomes, Vera B. Coutinho, Maria José C. Schuetz, Vânia S. Cavalcante, M. Edileuza F. Brito, Helio B. Coutinho   +7 more
doaj   +1 more source

Decoding a neural circuit controlling global animal state in C. elegans

eLife, 2015
Brains organize behavior and physiology to optimize the response to threats or opportunities. We dissect how 21% O2, an indicator of surface exposure, reprograms C.
Patrick Laurent, Zoltan Soltesz, Geoffrey M Nelson, Changchun Chen, Fausto Arellano-Carbajal, Emmanuel Levy, Mario de Bono   +6 more
doaj   +1 more source

miR-153 regulates SNAP-25, synaptic transmission, and neuronal development. [PDF]

PLoS ONE, 2013
SNAP-25 is a core component of the trimeric SNARE complex mediating vesicle exocytosis during membrane addition for neuronal growth, neuropeptide/growth factor secretion, and neurotransmitter release during synaptic transmission.
Chunyao Wei, Elizabeth J Thatcher, Abigail F Olena, Diana J Cha, Ana L Perdigoto, Andrew F Marshall, Bruce D Carter, Kendal Broadie, James G Patton   +8 more
doaj   +1 more source

Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]

, 1993
The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
B. Marquèze-Pouey, Bergmann, Betz, D. Grabs, Goldman-Rakic, Graybiel, H. Betz, Heimer, Hsu, I. Reisert, Iñiguez, Jahn, Jahn, Kita, Knaus, Lahr, Lauder, Leube, Lindefors, M. Bergmann, M. Gratzl, Marquèze-Pouey, Mugnaini, Newman-Gage, Olson, P. Knaus, Reiner, Reisert, Smith, Specht, Specht, Südhof, Thomas, Vernier, W. Ovtscharoff, Wiedenmann, Wilson   +36 more
core   +1 more source

The Role of Snapin in Neurosecretion: Snapin Knock-Out Mice Exhibit Impaired Calcium-Dependent Exocytosis of Large Dense-Core Vesicles in Chromaffin Cells

Journal of Neuroscience, 2005
Identification of the molecules that regulate the priming of synaptic vesicles for fusion and the structural coupling of the calcium sensor with the soluble N-ethyl maleimide sensitive factor adaptor protein receptor (SNARE)-based fusion machinery is ...
Jin-hua Tian, Zhengxing Wu, Michael Unzicker, Li Lu, Qian Cai, Cuiling Li, C. Schirra, U. Matti, D. Stevens, C. Deng, J. Rettig, Zu-Hang Sheng   +11 more
semanticscholar   +1 more source

Fluorescent β-Blockers as Tools to Study Presynaptic Mechanisms of Neurosecretion

Pharmaceuticals, 2011
Several, if not all adrenergic β-blockers (β-Bs), accumulate progressively inside secretory vesicles in a time- and concentration-dependent manner, and could be considered to be false neurotransmitters. This transmitter effect is most likely unrelated to
Jose D. Machado, Beatriz Beltran, Romen Carrillo, Tomas Martin, Victor S. Martin, Ricardo Borges   +5 more
doaj   +1 more source

The phytochemical composition of Melia volkensii and its potential for insect pest management [PDF]

, 2020
Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable alternatives for insect pest management.
Backx, Simon, Jaoko, Victor, Magomere, Titus, Mangelinckx, Sven, Mulatya, Jackson, Olubayo, Florence, Smagghe, Guy, Taning, Nji Tizi Clauvis, Van den Abeele, Jan, Werbrouck, Stefaan   +9 more
core   +2 more sources

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source

Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans

Journal of Neuroscience, 2004
IA-2 (insulinoma-associated protein 2), a major autoantigen in type 1 diabetes, is a receptor-tyrosine phosphatase-like protein associated with the membrane of secretory granules of neural and endocrine-specific cells.
T. Cai, T. Fukushige, A. Notkins, M. Krause   +3 more
semanticscholar   +1 more source