Purinergic signalling: past, present and future [PDF]
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock
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PC-12 Cell Line as a Neuronal Cell Model for Biosensing Applications
PC-12 cells have been widely used as a neuronal line study model in many biosensing devices, mainly due to the neurogenic characteristics acquired after differentiation, such as high level of secreted neurotransmitter, neuron morphology characterized by ...
Daniela Oprea +3 more
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Central release of nitric oxide mediates antinociception induced by aerobic exercise [PDF]
Nitric oxide (NO) is a soluble gas that participates in important functions of the central nervous system, such as cognitive function, maintenance of synaptic plasticity for the control of sleep, appetite, body temperature, neurosecretion, and ...
G.S. Galdino, I.D. Duarte, A.C. Perez
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Molecular Weight Distribution of Proteins Synthesized in Single, Identified Neurons of Aplysia [PDF]
Parietovisceral ganglia from Aplysia californica were incubated in medium containing leucine-3H. Single, identified nerve cell somas were isolated from the ganglia, and their proteins extracted and separated by electrophoresis on 5% SDS-polyacrylamide ...
Wilson, David L.
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Neurosecretion: what can we learn from chromaffin cells
Many of the molecular players in the stimulus-secretion chain are similarly active in neurosecretion and catecholamine release. Therefore, studying chromaffin cells uncovered many details of the processes of docking, priming, and exocytosis of vesicles ...
E. Neher
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Timing feedback-inhibition of the male reproductive hormone axis [PDF]
Hormonal methods of male contraception have addressed feedback-inhbition of the cascade of hormones that has evolved to regulate sperm production but high concentrations of testosterone (T) in the blood have not worked satisfactorily.
Amit Misra +4 more
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Using microarrays to facilitate positional cloning: identification of tomosyn as an inhibitor of neurosecretion. [PDF]
Forward genetic screens have been used as a powerful strategy to dissect complex biological pathways in many model systems. A significant limitation of this approach has been the time-consuming and costly process of positional cloning and molecular ...
Michael Dybbs +2 more
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Advances in Understanding of Structural Reorganization in the Hypothalamic Neurosecretory System
The hypothalamic neurosecretory system synthesizes neuropeptides in hypothalamic nuclei and releases them from axonal terminals into the circulation in the neurohypophysis (NH) and median eminence (ME). This system plays a crucial role in regulating body
Seiji Miyata
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Synaptic and peptidergic connectome of a neurosecretory center in the annelid brain
Neurosecretory centers in animal brains use peptidergic signaling to influence physiology and behavior. Understanding neurosecretory center function requires mapping cell types, synapses, and peptidergic networks.
Elizabeth A Williams +7 more
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In memoriam Michael R. Warburg [PDF]
Hornung, Elizabeth (2015): IN MEMORIAM MICHAEL R. WARBURG (31 May 1931, Berlin - 9 February 2014, Haifa). Acta Zoologica Academiae Scientiarum Hungaricae 61 (1): 1-2, DOI: 10.17109/AZH.61.1.1.2015, URL: http://dx.doi.org/10.17109/azh.61.1.1 ...
Hornung, Erzsébet
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