Results 201 to 210 of about 16,231 (234)
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Neurosteroids: recent findings
Brain Research Reviews, 2001The term neurosteroid applies to those steroids that are synthesized in the nervous system, from cholesterol or other blood-borne steroidal precursors, and that accumulate in the nervous system to levels that are at least in part independent from steroidogenic gland secretion.
E, Plassart-Schiess, E E, Baulieu
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Neurochemical Journal, 2021
Abstract—Neurosteroids are steroids that rapidly alter neuronal excitability by interacting with cell surface receptors, mainly the GABA/A receptor complex. Neurosteroids are synthesized both in the central nervous system and in peripheral tissues, from which they enter the brain via systemic blood circulation.
D. A. Zhukov, E. P. Vinogradova
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Abstract—Neurosteroids are steroids that rapidly alter neuronal excitability by interacting with cell surface receptors, mainly the GABA/A receptor complex. Neurosteroids are synthesized both in the central nervous system and in peripheral tissues, from which they enter the brain via systemic blood circulation.
D. A. Zhukov, E. P. Vinogradova
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The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells.
Steroids, 2019Glioblastoma (GBM) is the most aggressive local brain tumor and effective treatments are lacking. Many studies have proposed an important participation of steroid hormones in the development of gliomas.
Pinacho-Garcia Luis Manuel +5 more
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Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2019
In this work, a novel strategy of stable isotope labeling derivatization (SILD) combined with magnetic dispersive solid-phase extraction (MDSPE), has been proposed for simultaneous monitoring of neurosteroids changes linked to Parkinson's disease (PD) by
Yanqiu Xu +7 more
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In this work, a novel strategy of stable isotope labeling derivatization (SILD) combined with magnetic dispersive solid-phase extraction (MDSPE), has been proposed for simultaneous monitoring of neurosteroids changes linked to Parkinson's disease (PD) by
Yanqiu Xu +7 more
semanticscholar +1 more source
General and Comparative Endocrinology, 2014
Bargmann-Scharrer's discovery of "neurosecretion" in the first half of the 20th century has since matured into the scientific discipline of neuroendocrinology. Identification of novel neurohormones, such as neuropeptides and neurosteroids, is essential for the progress of neuroendocrinology.
Kazuyoshi, Tsutsui, Shogo, Haraguchi
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Bargmann-Scharrer's discovery of "neurosecretion" in the first half of the 20th century has since matured into the scientific discipline of neuroendocrinology. Identification of novel neurohormones, such as neuropeptides and neurosteroids, is essential for the progress of neuroendocrinology.
Kazuyoshi, Tsutsui, Shogo, Haraguchi
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Neurosteroids: non‐genomic pathways in neuroplasticity and involvement in neurological diseases
Pharmacology and Therapeutics, 2018Neurosteroids are neuroactive brain‐born steroids. They can act through non‐genomic and/or through genomic pathways. Genomic pathways are largely described for steroid hormones: the binding to nuclear receptors leads to transcription regulation ...
M. Schverer +4 more
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2001
Neurosteroid production may be a mechanism to counteract the negative effects of stress and return organisms toward homeostasis. Stress induces an increase in neurosteroid production. Neurosteroids affect two of the most widely distributed neurotransmitter and receptor systems in the central nervous system (CNS): gamma-aminobutyric acid (GABA) and ...
S R, Engel, K A, Grant
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Neurosteroid production may be a mechanism to counteract the negative effects of stress and return organisms toward homeostasis. Stress induces an increase in neurosteroid production. Neurosteroids affect two of the most widely distributed neurotransmitter and receptor systems in the central nervous system (CNS): gamma-aminobutyric acid (GABA) and ...
S R, Engel, K A, Grant
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Neurosteroids: Biosynthesis and Function
1994The term "neurosteroids" applies to those steroids that are both synthesized in the nervous system, either de novo from cholesterol or from steroid hormone precursors, and that accumulate in the nervous system to levels at least in part independent of steroidogenic gland secretion rates.
P, Robel, E E, Baulieu
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Neurosteroids and Sporadic Alzheimers Disease
Current Alzheimer Research, 2008A reduction of neurosteroids in the brain may initiate sporadic Alzheimer's disease (AD) which comprises >99% of all AD cases. AD research is currently focused on aberrant amyloid precursor protein (APP) processing and the hyper-phosphorylation of tau protein. This is based on early-onset genetic and pathological observations clearly showing that these
Barry, Guy, Ross, Ian L.
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European Archives of Psychiatry and Clinical Neuroscience, 2022
R. Rupprecht +9 more
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R. Rupprecht +9 more
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