Results 21 to 30 of about 103 (84)

Age and Sex as Determinants of Acute Domoic Acid Toxicity in a Mouse Model

Toxins, 2023
The excitatory neurotoxin domoic acid (DA) consistently contaminates food webs in coastal regions around the world. Acute exposure to the toxin causes Amnesic Shellfish Poisoning, a potentially lethal syndrome of gastrointestinal- and seizure-related ...
Alicia M. Hendrix, Kathi A. Lefebvre, Emily K. Bowers, Rudolph Stuppard, Thomas Burbacher, David J. Marcinek   +5 more
doaj   +1 more source

Prominent Human Health Impacts from Several Marine Microbes: History, Ecology, and Public Health Implications

International Journal of Microbiology, 2011
This paper overviews several examples of important public health impacts by marine microbes and directs readers to the extensive literature germane to these maladies.
P. K. Bienfang, S. V. DeFelice, E. A. Laws, L. E. Brand, R. R. Bidigare, S. Christensen, H. Trapido-Rosenthal, T. K. Hemscheidt, D. J. McGillicuddy, D. M. Anderson, H. M. Solo-Gabriele, A. B. Boehm, L. C. Backer   +12 more
doaj   +1 more source

Chemiluminescent Receptor Binding Assay for Ciguatoxins and Brevetoxins Using Acridinium Brevetoxin-B2

Toxins, 2019
Ciguatera is the term for poisoning resulting from eating fish from tropical or subtropical regions. The causative toxins collectively named ciguatoxins (CTXs) widely differ in structures depending on their geographic origins, which range from the ...
Kazuya Murata, Takeshi Yasumoto
doaj   +1 more source

Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels

Toxins, 2019
Brevetoxins are produced by dinoflagellates such as Karenia brevis in warm-water red tides and cause neurotoxic shellfish poisoning. They bind to voltage-gated sodium channels at neurotoxin receptor 5, making the channels more active by shifting the ...
Keiichi Konoki, Daniel G. Baden, Todd Scheuer, William A. Catterall   +3 more
doaj   +1 more source

Discovery of a Potential Human Serum Biomarker for Chronic Seafood Toxin Exposure Using an SPR Biosensor

Toxins, 2019
Domoic acid (DA)-producing harmful algal blooms (HABs) have been present at unprecedented geographic extent and duration in recent years causing an increase in contamination of seafood by this common environmental neurotoxin. The toxin is responsible for
Kathi A. Lefebvre, Betsy Jean Yakes, Elizabeth Frame, Preston Kendrick, Sara Shum, Nina Isoherranen, Bridget E. Ferriss, Alison Robertson, Alicia Hendrix, David J. Marcinek, Lynn Grattan   +10 more
doaj   +1 more source

Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cells.

PLoS ONE, 2008
Ciguatoxins and brevetoxins are neurotoxic cyclic polyether compounds produced by dinoflagellates, which are responsible for ciguatera and neurotoxic shellfish poisoning (NSP) respectively. Recently, brevenal, a natural compound was found to specifically
César Mattei, Peter J Wen, Truong D Nguyen-Huu, Martha Alvarez, Evelyne Benoit, Andrea J Bourdelais, Richard J Lewis, Daniel G Baden, Jordi Molgó, Frédéric A Meunier   +9 more
doaj   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

Neurotoxic Alkaloids: Saxitoxin and Its Analogs

Marine Drugs, 2010
Saxitoxin (STX) and its 57 analogs are a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs). PSTs are the causative agents of paralytic shellfish poisoning (PSP) and are mostly associated with marine ...
Troco K. Mihali, Michelle C. Moffitt, Brett A. Neilan, Maria Wiese, Paul M. D’Agostino   +4 more
doaj   +1 more source

Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates

Marine Drugs, 2013
Numerous species of marine dinoflagellates synthesize the potent environmental neurotoxic alkaloid, saxitoxin, the agent of the human illness, paralytic shellfish poisoning.
Kjetill S. Jakobsen, Shauna A. Murray, Russell J. S. Orr, Anke Stüken   +3 more
doaj   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source