Results 41 to 50 of about 33,769 (117)
Cefepime-induced neurotoxicity [PDF]
Journal of Neurocritical Care, 2019 Cefepime, a widely used fourth-generation cephalosporin, has been reported to cause neurotoxicity because it crosses the blood-brain barrier. Although cefepime-induced neurotoxicity (CIN) occurs in patients with renal dysfunction administered a high ...
Se-Jin Lee
doaj +1 more source
Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics
Heliyon, 2023 Local anesthetics are frequently used by dentists to relieve localized discomfort of the patient and improve treatment conditions. The risk of paresthesia after local anesthesia is frequently encountered in dental clinics.
Yong-zhen Tan +4 more
doaj
Child with acute methotrexate related neurotoxicity: Can diffusion weighted MRI help??
The Egyptian Journal of Radiology and Nuclear Medicine, 2015 Background: Methotrexate is widely used chemotherapy especially in pediatric hematological malignancy. It may associate with acute neurotoxicity.
Ayda A. Youssef +2 more
doaj +1 more source
Scenarios for protein aggregation: Molecular Dynamics simulations and Bioinformatic Analysis [PDF]
arXiv, 2006 The need to understand the assembly kinetics of fibril formation has become urgent because of the realization that soluble oligomers of amyloidogenic peptides may be even more neurotoxic than the end product, namely, the amyloid fibrils. In order to fully understand the routes to fibril formation one has to characterize the major species in the ...
arxiv
Clinical Medicine Insights: Case Reports, 2019 Transient contrast neurotoxicity is a rare but well-recognized complication of angiography that is due to neurotoxicity of the contrast agent. Patients with renal dysfunction may be inclined to develop contrast medium neurotoxicity due to delayed ...
Ersin Çagri Şimşek +6 more
doaj +1 more source
Effect of Metals on Kinetic Pathways of Amyloid-\b{eta} Aggregation [PDF]
arXiv, 2017 Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimers disease through a variety of mechanisms including increased amyloid \b{eta} affinity and redox effects. Recent reports have demonstrated that the amyloid \b{eta} monomer does not necessarily travel through a definitive intermediary en-route to a stable amyloid
arxiv
A reaction-diffusion model for the progression of Parkinson's disease [PDF]
arXiv, 2017 The temporal and spatial development of Parkinson's disease has been characterised as the progressive formation of {\alpha}-synuclein aggregations through susceptible neuronal pathways. This article describes a new model for this progression mechanism in which Parkinsonian damage moves over time through the nervous system by the combined effect of the ...
arxiv
Cyclooxygenase inhibition in ischemic brain injury [PDF]
Current Pharmaceutical Design 2008; 14(14):1401-1418, 2008 Neuroinflammation is one of the key pathological events involved in the progression of brain damage caused by cerebral ischemia. Metabolism of arachidonic acid through cyclooxygenase (COX) enzymes is known to be actively involved in the neuroinflammatory events leading to neuronal death after ischemia.
arxiv
Negative myoclonus as a manifestation of cefepime neurotoxicity
Clinical Case ReportsKey Clinical Message Negative myoclonus may present in the early stages of cefepime neurotoxicity. Cefepime neurotoxicity typically presents as reduced consciousness, myoclonus, and seizures; however, negative myoclonus is uncommon.
Daichi Umemoto +2 more
doaj +1 more source
Annals of General Psychiatry, 2019 Background Although kidney transplantation is the best treatment option for chronic kidney disease, the accompanying immunosuppressive treatment can induce severe neurotoxicity presenting, on rare occasions, as psychosis.
Eun Hyun Seo +3 more
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