Results 1 to 10 of about 25,999 (347)
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy [PDF]
Nature Reviews Immunology, 2021 A paradigm shift has recently occurred in the field of cancer therapeutics. Traditional anticancer agents, such as chemotherapy, radiotherapy and small-molecule drugs targeting specific signalling pathways, have been joined by cellular immunotherapies based on T cell engineering.
Emma Morris +3 more
openalex +4 more sources
The role of neuroimaging in neurotoxicity after chimeric antigen receptor T-cell therapy [PDF]
Therapeutic Advances in Neurological DisordersChimeric antigen receptor T-cell (CAR-T) therapy has become an established treatment for several haematological malignancies in relapse and is being evaluated for new indications.
Arian Lasocki +3 more
doaj +2 more sources
Stiff Person Syndrome Misdiagnosed as Oxaliplatin Induced Neurotoxicity [PDF]
Journal of Pharmaceutical Technology, Research and Management, 2021 Introduction: Stiff person syndrome is characterized by muscle rigidity that waxes and wanes along with concurrent spasms. The symptoms of the stiff-person syndrome were identical to those of oxaliplatin side effects. Methods: This was a case report of a 65-year-old man who was diagnosed with stiff-person syndrome.
K A Shaima +4 more
openalex +2 more sources
Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT): A Review [PDF]
Clinical Neuropharmacology, 2022 Persistent sequelae of lithium intoxication gained clinical attention in the 1980s and were named Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT). The authors review the published cases of SILENT reported in the literature and discuss various clinical manifestations.The authors' inclusion criteria included persistence of sequelae ...
Cátia Fernandes Santos, R. Gomes
openalex +3 more sources
Paraneoplastic Neurological Syndromes: Advances and Future Perspectives in Immunopathogenesis and Management [PDF]
AntibodiesParaneoplastic neurological syndromes (PNSs) are immune-mediated disorders caused by an antitumor response that cross-reacts with the nervous system, leading to severe and often irreversible neurological disability. Once considered exceedingly rare, PNSs
Stoimen Dimitrov +4 more
doaj +2 more sources
Neurotoxic Syndromes in Marine Poisonings a Review
Iranian South Medical Journal, 2014 Background: Marine neurotoxins as of Marine biotoxins are natural toxins that produced mainly by dinoflagellates, diatoms and several species of invertebrates and fish. Marine poisoning results from the ingestion of marine animals contain these toxins and causes considerable adverse effects.
Gholam Hossein Mohebbi +2 more
openalex +2 more sources
Immune effector cell-associated neurotoxicity syndrome (ICANS)
, 2023 Frank Gaillard
+4 more sources
Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer [PDF]
Korean Journal of Anesthesiology, 2022 Background The depth of anesthesia is an essential factor in surgical prognosis. The neurotoxic effect of chemotherapeutic drugs affects the sensitivity to anesthetics.
Seunghee Ki +5 more
doaj +1 more source
Frontiers in Neurology, 2022 Cancer immunotherapy represents a novel anticancer strategy that acts directly on the immune system, promoting its activation toward cancer cells to enhance its natural ability to fight cancer.
Umberto Pensato +2 more
doaj +1 more source