Results 101 to 110 of about 25,999 (347)

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Acute ketoprofen neurotoxicity in spinal cord of rats [PDF]

Einstein (São Paulo), 2008
Objective: To evaluate possible spinal cord injury in rats followingdifferent doses of intrathecal ketoprofen. Methods: Animalswere divided into four groups of five rats each; 10 μl of anintrathecal solution were injected into the L6-S1 ...
Eric Roger Wroclawski, Maria Tereza Gianotti Galupo, Irimar de Paula Posso, Desiré Carlos Callegari   +3 more
doaj  

Oxaliplatin neurotoxicity involves peroxisome alterations. PPARγ agonism as preventive pharmacological approach.

PLoS ONE, 2014
The development of neuropathic syndromes is an important, dose limiting side effect of anticancer agents like platinum derivates, taxanes and vinca alkaloids.
Matteo Zanardelli, Laura Micheli, Lorenzo Cinci, Paola Failli, Carla Ghelardini, Lorenzo Di Cesare Mannelli   +5 more
doaj   +1 more source

The bilirubin albumin ratio in the management of hyperbilirubinemia in preterm infants to improve neurodevelopmental outcome: A randomized controlled trial - BARTrial [PDF]

, 2014
Background and Objective: High bilirubin/albumin (B/A) ratios increase the risk of bilirubin neurotoxicity. The B/A ratio may be a valuable measure, in addition to the total serum bilirubin (TSB), in the management of hyperbilirubinemia.
Benders, J. (Jos), Bos, A.F. (Arend), Braeckel, K.N.J.A. (Koen N. J.) van, Buijs, J. (Jan), Dijk, P.H. (Peter), Fetter, W.P.F. (Willem), Govaert, P. (Paul), Groot Jebbink, L.J.M. (Liesbeth), Hulzebos, C.V. (Christian), Imhoff, D.E. (Deirdre) van, Korbeeck-van Hof, K.K.M. (Karen K.), Krabbe, P.F.M. (Paul), Laarman, G-J. (GertJan), Liem, D. (Djien), Lingen, R.A. (Richard), Lopriore, E., Mansvelt, P. (Petri), Mulder, T.L.M. (Twan L.), Nuytemans, K., Offringa, M. (Martin), Quik, E.H. (Elise), Ruiter, S.A.J. (Selma A.), Toledo-Eppinga, L. (Letty) van, Vliet, I. (Ineke) van, Wassenaer-Leemhuis, A.G. (Aleid) van, Wolfs, C. (Cecile)   +25 more
core   +1 more source

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

BMEMat, EarlyView.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan, Yuchan Xue, Miao Zhang, Zihao Zhang, Shiyu Peng, Minghao Sui, Han Ding, Yingying Nie, Yuemin Feng, Le Wang, Tianru Zhang, Mingchuan Yu, He Xia, Hong Liu, Qiang Zhu, Songbo Zhao   +15 more
wiley   +1 more source

A Novel Patient‐Specific Landmark‐Guided Approach for Intramuscular Botulinum Neurotoxin Injections Into the Rotator Cuff: A Cadaveric Study

Clinical Anatomy, EarlyView.
ABSTRACT Myofascial pain syndrome (MFPS) causes chronic shoulder pain. Supraspinatus and infraspinatus, rotator cuff muscles innervated by the suprascapular nerve, are commonly affected. Intramuscular botulinum neurotoxin (BoNT) injections near motor points (i.e., visible nerve branch entry sites used as a proxy for motor endplates) are an effective ...
Dave Osinachukwu Duru, David Kwan Ryung Lee, Gavin E. Jarvis, Niel Kang, Salma Chaudhury, Cecilia Brassett   +5 more
wiley   +1 more source

Management of Occupational Manganism: Consensus of an Experts' Panel [PDF]

, 2005
Studies and Research Projects / Report R-417, Montréal, IRSST http://www.irsst.qc.ca/en/_publicationirsst_100134.html (Lucchini R was a member of the Expert ...
Asselin P, DeWals P, LUCCHINI R., Malo S, Nadeau D, Ostiguy C   +5 more
core  

Cognitive impairment in HIV and HCV co-infected patients: a systematic review and meta-analysis [PDF]

, 2016
Cognitive impairment has been well documented in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited.
Bucur, Mihaela, Fialho, Renata, Fisher, Martin, Pereira, Marco, Rusted, Jennifer, Whale, Richard   +5 more
core   +1 more source

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

An aggravated return-to-work case of organic solvent induced chronic toxic encephalopathy

Annals of Occupational and Environmental Medicine, 2018
Background Organic solvent-induced chronic toxic encephalopathy (CTE) is known as a non-progressive disorder that does not progress after diagnosis. The authors present a case those symptoms worsened after continued exposure to organic solvent after ...
Sangyun Seo, Jungwon Kim
doaj   +1 more source