Results 191 to 200 of about 90,679 (311)

Observational Evaluation of Muscle Echointensity and EMG Insertional Activity in Poststroke Spasticity. [PDF]

Muscle Nerve
Reebye R, Boissonnault È, Jeon A, Filippetti M, McKernan G, Adenaiye OO, Picelli A, Munin MC.   +7 more
europepmc   +1 more source

Genetic diversity within the botulinum neurotoxin-producing bacteria and their neurotoxins.

Toxicon, 2015
K. Hill, Gary Xie, B. Foley, Theresa J. Smith   +3 more
semanticscholar   +1 more source

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add‐on trials in drug‐resistant focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Most antiseizure medications (ASMs) have been discovered by testing in animal models, which are generally thought to predict antiseizure activity in patients. However, it is not known whether any of these models (or a combination of models) can predict whether a novel ASM exhibits higher clinical efficacy in focal drug‐resistant ...
Wolfgang Löscher, Pavel Klein
wiley   +1 more source

Investigating the dual nature of <i>Clostridium botulinum</i>: pathogenic mechanisms and therapeutic potentials. [PDF]

Infez Med
Soleymanpour K, Zeinalzadeh E, Ganbarov K, Asgharzadeh M, Kafil HS.   +4 more
europepmc   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

Clostridium botulinum neurotoxin [PDF]

Microbiological Reviews, 1980
openaire   +2 more sources

Response by Chirumbolo to "Rare Localized Adverse Reaction to Botulinum Toxin Type A in a Patient Without Allergic History: A Case Report" by Muner et al. [PDF]

Aesthet Surg J Open Forum
Chirumbolo S.
europepmc   +1 more source

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

Epilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu, Yujiao Yang, Pan Gong, Kun Lv, Yilin Liu, Chongyang Tang, Xiongfei Wang, Lixin Cai, Qingzhu Liu, Yuwu Jiang, Taoyun Ji, Guoming Luan   +11 more
wiley   +1 more source

Botulinum toxin A for post-stroke spasticity: Insights from the French National Hospital Discharge Database (2015-2023). [PDF]

Eur Stroke J
Bensmail D, Forestier A, Loze JY, Karam P.   +3 more
europepmc   +1 more source

Modeling temporal lobe epilepsy with hippocampal sclerosis in rats using the selective neurotoxin stable substance P‐saporin

Epilepsia, EarlyView.
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta, Mitchell T. Kesler, Morris H. Scantlebury, Robert S. Sloviter, G. Campbell Teskey   +4 more
wiley   +1 more source