Results 251 to 260 of about 65,558 (345)

Botulinum Toxin: A Comprehensive Review of Its Molecular Architecture and Mechanistic Action. [PDF]

Int J Mol Sci
Kumar R, Singh BR.
europepmc   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Iatrogenic botulism after intragastric botulinum neurotoxin injections - a major outbreak. [PDF]

Neurol Res Pract
Goerttler T, Dorner MB, van der Linden C, Kienitz R, Petrik S, Blechinger S, Spickschen J, Betz IR, Hinrichs C, Steindl D, Weber F, Musacchio T, Wunderlich G, Rueger MA, Barbe MT, Dafsari H, Demir S, Lapa S, Zeiner PS, Strzelczyk A, Tinnemann P, Kleine C, Totzeck A, Klebe S, Mikolajewska A, Dorner BG, Fertl E, Grefkes-Hermann C, Fink G, Kleinschnitz C, Hagenacker T.   +30 more
europepmc   +1 more source

Tau‐targeting nanoparticles for treatment of Alzheimer's disease

Exploration, EarlyView.
Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar, Mohd Ahmar Rauf, Hosam Abdelhady, Arun K. Iyer   +3 more
wiley   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Persistent Oscillating Vertigo From Extracranial Venous Compression. [PDF]

Otol Neurotol Open
Cha YH, Gharib M, Chan K, Karam J.
europepmc   +1 more source

Purification and characterization of a protease from Clostridium botulinum type A that nicks single-chain type A botulinum neurotoxin into the di-chain form

, 1990
Michael L. Dekleva, Bibhuti R. DasGupta
openalex   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

Preventive Effects of Botulinum Neurotoxin Long-Term Therapy: Comparison of the 'Experienced' Benefits and 'Suspected' Worsening Across Disease Entities. [PDF]

J Clin Med
Hefter H, Samadzadeh S.
europepmc   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source