Results 261 to 270 of about 105,668 (383)

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

Chemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos, Marie Demonceaux, Lucia Emanueli Schimith, Marine Goux, Claude Solleux, Ana Luiza Muccillo‐Baisch, Bruno Dutra Arbo, Corinne Andre‐Miral, Mariana Appel Hort   +8 more
wiley   +1 more source

Autonomic Dysfunction and Blood Pressure Variability in Botulinum Intoxication: A Prospective Observational Study from a Single-Center Italian Outbreak. [PDF]

Toxins (Basel)
Miceli G, Cassataro G, Volpe V, Fertitta E, Canale C, Tomaiuolo L, Blasco M, Stella M, Velardo M, Renda M.   +9 more
europepmc   +1 more source

Regulated Secretion Is Impaired in AtT-20 Endocrine Cells Stably Transfected with Botulinum Neurotoxin Type A Light Chain [PDF]

, 1997
Fernando Aguado, Lourdes Gombau, Glòria Majó, Jordi Marsal, Jerónimo Blanco, Juan Blasi   +5 more
openalex   +1 more source

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi, Güler Durmuş, Mustafa Ceylan, Şuheda Yıldırım, Ümit M. Koçyiğit, Ümit Yırtıcı, Volkan Eyüpoğlu   +6 more
wiley   +1 more source

Histopathological changes of the buccal mucosa and skin after botulinum neurotoxin intramuscular injection in rats (immunohistochemical study). [PDF]

BMC Oral Health
Hassan GS, Abouzaid BH, Saleh RG.
europepmc   +1 more source

An overview on the origin and production of tetrodotoxin, a potent neurotoxin

Journal of Applied Microbiology, 2015
S. Jal, S. S. Khora
semanticscholar   +1 more source

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

ChemBioChem, EarlyView.
Previous studies reveal an unexpected tendency for amyloid aggregation in specific regions of the C‐terminal domain (CTD) of nucleophosmin 1 (NPM1), a nucleolar chaperone involved in acute myeloid leukemia (AML). Herein, several peptide analogs of NPM1264‐277 (amyloid core) with conservative substitutions are designed and evaluated through biophysical ...
Daniele Florio, Sara La Manna, Giada Raffaella Fiore, Valentina Roviello, Giuliano Castellano, Sossio Fabio Graziano, Anna Maria Malfitano, Daniela Marasco   +7 more
wiley   +1 more source

Assessing the Efficacy of Botulinum Toxin in Treating Neuropathic Pain: A Report of Two Cases. [PDF]

Cureus
Cruz LL, Mota SJ, Catarino IP, Cardoso HP.   +3 more
europepmc   +1 more source

Spotlight commentary: Treatment of multidrug‐resistant Gram‐negative infections in the era of growing antimicrobial resistance

British Journal of Clinical Pharmacology, EarlyView.
Luka Bielen, Andro Vujević, Luka Csenar
wiley   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

ChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang, Nataliia Lukianenko, Ja‐Hyun Baik, Yun Kyung Kim, Sungsu Lim   +4 more
wiley   +1 more source