Results 11 to 20 of about 191,466 (342)
Targeted Sensors for Glutamatergic Neurotransmission [PDF]
Biophysical Journal, 2021 AbstractOptical report of neurotransmitter release allows visualization of excitatory synaptic transmission. Sensitive genetically-encoded glutamate reporters operating with a range of affinities and emission wavelengths are available. However, without targeting to synapses, the specificity of the fluorescent signal is uncertain, compared to sensors ...
Christian Rosenmund +6 more
openaire +7 more sources
Phosphatidylserine, inflammation, and central nervous system diseases
Frontiers in Aging Neuroscience, 2022 Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple functions of the brain, such as activation of membrane signaling pathways ...
Xiaohua Ma +7 more
doaj +1 more source
Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease [PDF]
, 2008 Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affiliated sings.
Amin Geravand +4 more
core +2 more sources
Phosphatidic acid and neurotransmission [PDF]
Advances in Biological Regulation, 2017 Lipids play a vital role in the health and functioning of neurons and interest in the physiological role of neuronal lipids is certainly increasing. One neuronal function in which neuronal lipids appears to play key roles in neurotransmission. Our understanding of the role of lipids in the synaptic vesicle cycle and neurotransmitter release is becoming
Casey N. Barber, Daniel M. Raben
openaire +3 more sources
Dopamine drives Drosophila sechellia adaptation to its toxic host
eLife, 2014 Many insect species are host-obligate specialists. The evolutionary mechanism driving the adaptation of a species to a toxic host is, however, intriguing.
Sofía Lavista-Llanos +6 more
doaj +1 more source
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]
, 2017 Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P +11 more
core +1 more source
Adenovirus mediated gene transfer in organotypic brain slices
Neurobiology of Disease, 1995 A replication-defective adenovirus vector carrying the reporter gene encoding β-galactosidase was used to transfect organotypic slices maintained in culture for up to 1 month.
V. Ridoux +4 more
doaj +1 more source
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
Optical Modulation of Neurotransmission [PDF]
Biophysical Journal, 2013 The computational properties of an isolated neuron have been analyzed in detail by postsynaptic activation with caged compounds. However, new tools are needed to manipulate neurotransmission at individual synapses in order to understand how a neuron integrates physiological stimuli received from presynaptic neurons within a circuit.
Dirk Trauner +3 more
openaire +2 more sources