Results 101 to 110 of about 60,284 (256)

Rosa moschata ameliorates haloperidol-induced Parkinson's disease via reduction of neurodegeneration and oxidative stress

Asian Pacific Journal of Tropical Biomedicine
Objective: To investigate the effect of Rosa moschata (R. moschata) extract on haloperidol-induced Parkinson’s disease (PD) in rats. Methods: Haloperidol (1 mg/kg) was given to rats intraperitoneally for 3 weeks for induction of PD. R.
Badriyah S. Alotaibi, Uzma Saleem, Maryam Farrukh, Zunera Chaudhary, Nabia Anwar, Ifat Alsharif, Abdullah R. Alanzi, Tasahil S. Albishi, Fatima A. Jaber, Wedad Saeed Al-Qahtani, Muhammad Ajmal Shah   +10 more
doaj   +1 more source

cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia

Frontiers in Molecular Neuroscience, 2018
Dopamine is a brain neurotransmitter involved in the pathology of schizophrenia. The dopamine hypothesis states that, in schizophrenia, dopaminergic signal transduction is hyperactive.
Haitao Wang, Jiangping Xu, Philip Lazarovici, Remi Quirion, Wenhua Zheng   +4 more
doaj   +1 more source

Cerebral blood flow predicts differential neurotransmitter activity [PDF]

, 2018
Application of metabolic magnetic resonance imaging measures such as cerebral blood flow in translational medicine is limited by the unknown link of observed alterations to specific neurophysiological processes. In particular, the sensitivity of cerebral
Garry D Honey, Holiga, Štefan, Paulus M., Thomas Liu, Boak L., Nutt, David J, Steve C Williams, Dukart J., Hipp J., Myers J., Mehta M. A., Lauren Boak, Honey, Garry D, Williams, Steve C, Nutt D. J., Hawkins, Peter, Scott Schobel, Liu, Thomas, Merlo-Pich, Emilio, Zelaya, Fernando O, Joerg Hipp, Lingford-Hughes, Anne R, Fabio Sambataro, Muthukumaraswamy S., Zelaya, Fernando O; id_orcid, Myers, Jim, David J Nutt, Martin Paulus, Sambataro, Fabio, Peter Hawkins, McMillan R., Schobel, Scott, Emilio Merlo-Pich, Brown G., Liu T., Umbricht, Daniel, Štefan Holiga, Hipp, Joerg, Lingford-Hughes A. R., Rebecca McMillan, Anne R Lingford-Hughes, McMillan, Rebecca, Williams S. C., Muthukumaraswamy, Suresh, Mehta, Mitul A, Forsyth A., Honey G. D., Paulus, Martin, Merlo-Pich E., Hawkins P., Zelaya F. O., Chatham, Christopher, Daniel Umbricht, Jim Myers, Mitul A Mehta, Risterucci C., Holiga S., Juergen Dukart, Risterucci, Celine, Hawkins, Peter; id_orcid, Dukart, Juergen, Mehta, Mitul A; id_orcid, Suresh Muthukumaraswamy, Chatham C., Umbricht D., Forsyth, Anna, Christopher Chatham, Celine Risterucci, Brown, Gregory, Bertolino A., Bertolino, Alessandro, Gregory Brown, Alessandro Bertolino, Holiga, Štefan, Fernando O Zelaya, Schobel S., Boak, Lauren, Sambataro F., Anna Forsyth   +78 more
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin

Frontiers in Cellular Neuroscience, 2018
Serotonin or 5-hydroxytryptamine (5-HT) is an important neurotransmitter that is found in mammalian taste buds and can regulate the output of intragemmal signaling networks onto afferent nerve fibers.
Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huang, Liquan Huang   +8 more
doaj   +1 more source

Utilizing Calixarenes for Neurotransmitter Transport [PDF]

, 2017
Utilizing Calixarenes for Neurotransmitter Transport James Collins Biochemistry 0017 ...
Collins, James
core  

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Tinnitus and stress – from bedside to bench and back

Frontiers in Systems Neuroscience, 2012
The aim of this review is to focus the attention of clinicians and basic researchers on the association between emotional stress and tinnitus. Although tinnitus is an auditory symptom, its onset and progression often associates with emotional strain ...
Birgit eMazurek, Heidemarie eHaupt, Heidi eOlze, Agnieszka J. Szczepek   +3 more
doaj   +1 more source

Retinomorphic Visual Processing Enabled by Contact‐Engineered IGZO Optoelectronic Synaptic Memtransistors

Advanced Science, EarlyView.
Here, we present an optoelectronic synaptic memtransistor (OSMT) integrating photoresponsive IGZO with contact‐engineered HfO2, enabling electrically and optically tunable synaptic weights. The device demonstrates broad range of tunable conductance states and array‐level image processing, highlighting its potential for intelligent machine vision ...
Donghyun Kang, San Nam, Dayul Nam, In‐Soo Kim, Myung‐Gil Kim, Sung Kyu Park, Yong‐Hoon Kim   +6 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source