Results 111 to 120 of about 415,134 (313)

Cerebral blood flow predicts differential neurotransmitter activity

, 2017
Application of metabolic magnetic resonance imaging measures such as cerebral blood flow in translational medicine is limited by the unknown link of observed alterations to specific neurophysiological processes. In particular, the sensitivity of cerebral
Garry D Honey, Anne R Lingford-Hughes, Thomas Liu, Steve C Williams, Lauren Boak, Daniel Umbricht, Jim Myers, Mitul A Mehta, Scott Schobel, Juergen Dukart, Joerg Hipp, Suresh Muthukumaraswamy, Fabio Sambataro, David J Nutt, Christopher Chatham, Celine Risterucci, Martin Paulus, Peter Hawkins, Emilio Merlo-Pich, Gregory Brown, Alessandro Bertolino, Štefan Holiga, Fernando O Zelaya, Anna Forsyth, Rebecca McMillan   +24 more
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Editorial: Nongenomic influences of thyroid hormones and their metabolites in adults: a tribute to Mary B. Dratman

Frontiers in Endocrinology, 2023
Pradip K. Sarkar, Joseph V. Martin
doaj   +1 more source

DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

Acta Medica Iranica, 1998
Gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value.
D. Qujeq
doaj  

Carbon microelectrodes for the measurement of neurotransmitters with fast-scan cyclic voltammetry: methodology and applications

Frontiers in Bioengineering and Biotechnology
Carbon microelectrodes (CMEs) have emerged as pivotal tools in the field of neurochemical sensing, enabling precise, real-time monitoring of neurotransmitters in both research and clinical contexts.
Nadiah Alyamni, Nadiah Alyamni, Jandro L. Abot, Alexander G. Zestos   +3 more
doaj   +1 more source

SELF ADMINISTRATION OF OXYCODONE BY ADOLESCENT AND ADULT MICE AFFECTS STRIATAL NEUROTRANSMITTER RECEPTOR GENE EXPRESSION

, 2014
Illicit use of prescription opioid analgesics (e.g., oxycodone) in adolescence is a pressing public health issue. Our goal was to determine whether oxycodone self administration differentially affects striatal neurotransmitter receptor gene expression in
Mayer-Blackwell, B., Ott, J., Kreek, M. J., Ho, A., Schlussman, S. D., Butelman, E. R., Zhang, Y.   +6 more
core  

Neurotransmitter-associated enzymes and transporters identified in the H. verbana CNS transcriptome.

, 2018
Trees were produced in the same manner as in Fig 4. Transmitter-related subtypes and accession numbers can be found in Table 8.
Adam J. Northcutt (5540906), David J. Schulz (370833), Karen A. Mesce (5540909), Eva K. Fischer (3282660), Joshua G. Puhl (5540903)   +4 more
core   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

New Therapeutic Targets and Drugs for Schizophrenia Beyond Dopamine D2 Receptor Antagonists

Neuropsychiatric Disease and Treatment
Aineng Peng,1 Jianbo Chai,2 Haiyuan Wu,1 Bing Bai,3 Huihui Yang,1 Weizhi He,1 Yonghou Zhao2 1Heilongjiang University of Chinese Medicine, Harbin, 150040, People’s Republic of China; 2Heilongjiang Mental Hospital, Harbin, 150036, People’s Republic of ...
Peng A, Chai J, Wu H, Bai B, Yang H, He W, Zhao Y   +6 more
doaj  

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source