Results 121 to 130 of about 470,740 (429)
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
Advanced Healthcare Materials, EarlyView.This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source
The distribution of inhibitory neurons in the C. elegans connectome facilitates self-optimization of coordinated neural activity [PDF]
arXiv, 2020 The nervous system of the nematode soil worm Caenorhabditis elegans exhibits remarkable complexity despite the worm's small size. A general challenge is to better understand the relationship between neural organization and neural activity at the system level, including the functional roles of inhibitory connections.
arxiv
Advanced Healthcare Materials, EarlyView.This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey +5 more
wiley +1 more source
Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction [PDF]
, 2010 Synaptic dysfunction is widely thought to be a pathogenic precursor to neurodegeneration in Alzheimer’s disease (AD), and the extent of synaptic loss provides the best correlate for the severity of dementia in AD patients.
Ho, Angela +5 more
core +1 more source
Palmitoylation as a Functional Regulator of Neurotransmitter Receptors
Journal of Neural Transplantation and Plasticity, 2018 The majority of neuronal proteins involved in cellular signaling undergo different posttranslational modifications significantly affecting their functions.
V. Naumenko, E. Ponimaskin
semanticscholar +1 more source
Asymptotic and numerical analysis of a stochastic PDE model of volume transmission [PDF]
arXiv, 2018 Volume transmission is an important neural communication pathway in which neurons in one brain region influence the neurotransmitter concentration in the extracellular space of a distant brain region. In this paper, we apply asymptotic analysis to a stochastic partial differential equation model of volume transmission to calculate the neurotransmitter ...
arxiv
Advanced Materials, EarlyView.A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee +9 more
wiley +1 more source
The role of the neuromodulator adenosine in alcohols actions. [PDF]
, 1997 The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core
A tissue-like neurotransmitter sensor for the brain and gut
Nature, 2022 Jinxing Li +23 more
semanticscholar +1 more source
Neurotransmitter Switching in the Developing and Adult Brain.
Annual Review of Neuroscience, 2017 Neurotransmitter switching is the gain of one neurotransmitter and the loss of another in the same neuron in response to chronic stimulation. Neurotransmitter receptors on postsynaptic cells change to match the identity of the newly expressed ...
N. Spitzer
semanticscholar +1 more source