Results 181 to 190 of about 549,266 (339)

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Renal Denervation—“Gizmo Idolatry” Fact Checker

The Journal of Clinical Hypertension
Markus P. Schlaich, Murray D. Esler
doaj   +1 more source

Unveiling the rumen-microbiome-brain circuit: a unique dimension of gut-brain axis in ruminants. [PDF]

J Anim Sci Biotechnol
Joshi H, Bernard B, Lemley C, Wang Z, Fan P.   +4 more
europepmc   +1 more source

The Impairment of Trans Fatty Acids on Learning, Memory and Brain Amino Acid Neurotransmitters in Mice

, 2018
Tiantian Zhang, Ping Liu, Yu Sun, Na Ren, Shuang Nie   +4 more
openalex   +2 more sources

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

A study on neurotransmitter levels in rats with Tic disorder treated with aripiprazole. [PDF]

Front Neurosci
Chen HM, Wang Y, Xin YY, Sun D, Yang X, Liu ZS.   +5 more
europepmc   +1 more source

A rapid assay of amino acid neurotransmitters, Asp, Glu, Gly, taurine, and GABA in the brain within 5 min by high-performance liquid chromatography with electrochemical detection.

, 1991
Shigeo Murai, Hiroko Saito, Eiichi Abe, Yoshikatsu Masuda, Tadanobu Itoh   +4 more
openalex   +1 more source

Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

, 2020
Shreyas Bhat, Ali El‐Kasaby, Michael Freissmuth, Sonja Sučić   +3 more
openalex   +1 more source

Expanding neurotransmitters in the hypothalamic neurocircuitry for energy balance regulation [PDF]

, 2011
Yuanzhong Xu, Qingchun Tong
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source