Results 1 to 10 of about 172,320 (307)

Bioluminescence-based high-throughput screen identifies pharmacological agents that target neurotransmitter signaling in small cell lung carcinoma. [PDF]

PLoS ONE, 2011
BACKGROUND: Frontline treatment of small cell lung carcinoma (SCLC) relies heavily on chemotherapeutic agents and radiation therapy. Though SCLC patients respond well to initial cycles of chemotherapy, they eventually develop resistance.
Ma Reina D Improgo, Christopher W Johnson, Andrew R Tapper, Paul D Gardner   +3 more
doaj   +7 more sources

Brain-gut communication and potential applications of microecological treatments in stroke [PDF]

Frontiers in Neuroscience
Stroke is a cerebrovascular disease with high incidence rates, serious disability and increased mortality rates, thereby posing a serious threat to human health. The mechanisms of brain-gut communication have gradually emerged in recent times.
Mingzhu Gao, Yujie Zhou, Kaixin Zhang, Yang Ye, Zhijun Han, Qi Chen, Wentao Shi, Xiaojie Lu   +7 more
doaj   +2 more sources

Antiepileptic potential of ganaxolone [PDF]

Vojnosanitetski Pregled, 2017
nema
Janković Slobodan, Lukić Snežana
doaj   +1 more source

Plastic reorganisation of human motor cortex [PDF]

Vojnosanitetski Pregled, 2012
nema
Ilić Tihomir V., Ilić Nela V.
doaj   +1 more source

Reviewing the mechanism of propofol addiction

All Life, 2023
Propofol is widely used as a short-acting intravenous anaesthetic for the induction and maintenance of anaesthetic sedation. The application of propofol is expanding due to its advantages and the increasing demand for painless diagnosis and treatment ...
Tianhao Zhong, Yuyan Lin, Ruohuai Zhuge, Yujie Lin, Bingwu Huang, Ruifeng Zeng   +5 more
doaj   +1 more source

High concentration of dopamine treatment may induce acceleration of human sperm motility

Reproductive Medicine and Biology, 2022
Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno, Shouhei Kurata, Yuuki Hiradate, Kenshiro Hara, Hiroaki Yoshida, Kentaro Tanemura   +5 more
doaj   +1 more source

Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients

Medicina, 2020
Delirium, an acute alteration in mental status characterized by confusion, inattention and a fluctuating level of arousal, is a common problem in critically ill patients. Delirium prolongs hospital stay and is associated with higher mortality.
Wojciech Dabrowski, Dorota Siwicka-Gieroba, Malgorzata Gasinska-Blotniak, Sami Zaid, Maja Jezierska, Cezary Pakulski, Shawniqua Williams Roberson, Eugene Wesley Ely, Katarzyna Kotfis   +8 more
doaj   +1 more source

Neuropharmacologic modulation of the melatonergic system

Exploration of Neuroscience, 2023
The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating the internal clock of the body.
Utku Aykan, Muhammed Cihan Güvel, Gökçen Paykal, Canan Uluoglu   +3 more
doaj   +1 more source

Disminución del número de neuronas que expresan GABA en la corteza cerebral de ratones infectados con rabia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Algunos signos clínicos de la rabia y estudios experimentales previos sugieren que esta infección viral podría afectar al sistema GABAérgico. Objetivo. Evaluar el efecto de la infección con el virus de la rabia sobre la expresión de GABA en
Aura Caterine Rengifo, Orlando Torres-Fernández   +1 more
doaj   +1 more source

Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]

, 2017
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core   +3 more sources