Results 11 to 20 of about 3,321,798 (216)

The Relationship Between Dopamine Neurotransmitter Dynamics and the Blood-Oxygen-Level-Dependent (BOLD) Signal: A Review of Pharmacological Functional Magnetic Resonance Imaging

open access: yesFrontiers in Neuroscience, 2018
Functional magnetic resonance imaging (fMRI) is widely used in investigations of normal cognition and brain disease and in various clinical applications. Pharmacological fMRI (pharma-fMRI) is a relatively new application, which is being used to elucidate
Tyler J. Bruinsma   +14 more
doaj   +2 more sources

Effects of Z-338, a novel gastroprokinetic agent, on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema

open access: diamondJournal of Smooth Muscle Research, 2010
We investigated the effects of the novel gastroprokinetic agent Z-338 on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema (AP). Iontophoretic applications of acetylcholine (ACh), AMPA and NMDA increased, while GABA suppressed the firing rates of AP neurons recorded by extracellular electrodes.
Hironari Akaike   +5 more
openalex   +5 more sources

Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters

open access: hybridBiochemical and Biophysical Research Communications, 1990
The polypeptides PDGF, TGF alpha, and EGF have previously been shown by others to stimulate proliferation of fibroblasts and keratinocytes in the process of wound healing. Here we demonstrate that extracellular ATP, ADP or AMPPNP caused synergistic enhancement of DNA synthesis in 3T6 mouse fibroblasts and BALB/MK keratinocytes when combined with any of
Dingji Wang   +2 more
openalex   +4 more sources

Effects of various amino acids and their related agents in association with neurotransmitter substances on the morphine-induced Straub tail reaction in mice.

open access: bronzeChemical and Pharmaceutical Bulletin, 1978
Experiments were carried out in an attempt to elucidate the effects of various amino acids and their related agents in association with neurotransmitter substances on the morphine-induced Straub tail reaction (STR) in mice, using intracerebral injection technique.
Tsutomu Kameyama   +2 more
openalex   +5 more sources

Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review [PDF]

open access: yesBiomedicines
Postoperative neurocognitive dysfunction (PND) is a prevalent and debilitating complication in elderly surgical patients, characterized by persistent cognitive decline that negatively affects recovery and quality of life.
Tingting Wang   +7 more
doaj   +2 more sources

Current and Future Treatments in Alzheimer Disease: An Update

open access: yesJournal of Central Nervous System Disease, 2020
Disease-modifying treatment strategies for Alzheimer disease (AD) are still under extensive research. Nowadays, only symptomatic treatments exist for this disease, all trying to counterbalance the neurotransmitter disturbance: 3 cholinesterase inhibitors
Konstantina G Yiannopoulou   +1 more
doaj   +2 more sources

An Acetylcholinesterase-Based Chronoamperometric Biosensor for Fast and Reliable Assay of Nerve Agents

open access: yesSensors, 2013
The enzyme acetylcholinesterase (AChE) is an important part of cholinergic nervous system, where it stops neurotransmission by hydrolysis of the neurotransmitter acetylcholine.
Rene Kizek   +2 more
doaj   +2 more sources

Reviewing the mechanism of propofol addiction

open access: yesAll Life, 2023
Propofol is widely used as a short-acting intravenous anaesthetic for the induction and maintenance of anaesthetic sedation. The application of propofol is expanding due to its advantages and the increasing demand for painless diagnosis and treatment ...
Tianhao Zhong   +5 more
doaj   +1 more source

Antiepileptic potential of ganaxolone [PDF]

open access: yesVojnosanitetski Pregled, 2017
nema
Janković Slobodan, Lukić Snežana
doaj   +1 more source

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