Results 11 to 20 of about 3,509,514 (361)

Pharmacological properties of centrally‐administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain [PDF]

open access: bronzeBritish Journal of Pharmacology, 1973
Summary Centrally administered sodium diethyldithiocarbamate (DDC) produced hypothermia, central nervous depression and potentiation of the antinociceptive effect of morphine. These effects resemble those seen with centrally administered ouabain. Furthermore, the interactions of (+)‐amphetamine, desmethylimipramine and nialamide with DDC and ouabain ...
N.S. Doggett, P.S. Spencer
openalex   +4 more sources

Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Influenza presents a significant public health threat, as severe cases can lead to excessive inflammation and complications such as pneumonia or acute respiratory distress syndrome.
Yarou Gao   +13 more
doaj   +2 more sources

Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters

open access: hybridBiochemical and Biophysical Research Communications, 1990
The polypeptides PDGF, TGF alpha, and EGF have previously been shown by others to stimulate proliferation of fibroblasts and keratinocytes in the process of wound healing. Here we demonstrate that extracellular ATP, ADP or AMPPNP caused synergistic enhancement of DNA synthesis in 3T6 mouse fibroblasts and BALB/MK keratinocytes when combined with any of
Dingji Wang   +2 more
openalex   +3 more sources

RetS senses neurotransmitter norepinephrine and adrenergic agents to regulatePseudomonas aeruginosavirulence [PDF]

open access: green
AbstractBacterial cells employ diverse mechanisms to perceive and respond to host-associated molecules, coordinate intracellular signal transduction, and engage in interkingdom communications. In this study, we firstly discovered that the adrenergic antagonist dronedarone (DDR) effectively suppresses quorum sensing (QS) and pathogenesis of the ...
Ying Zhou   +11 more
openalex   +2 more sources

An Acetylcholinesterase-Based Chronoamperometric Biosensor for Fast and Reliable Assay of Nerve Agents

open access: yesSensors, 2013
The enzyme acetylcholinesterase (AChE) is an important part of cholinergic nervous system, where it stops neurotransmission by hydrolysis of the neurotransmitter acetylcholine.
Rene Kizek   +2 more
doaj   +2 more sources

Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism

open access: diamondJournal of Medical Biochemistry
Background: Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by neuroinflammation and amyloid deposition. Folic acid (FA), a B vitamin, may improve the course of AD by modulating inflammation and neuroprotection.
Jing Shao-wei   +8 more
openalex   +2 more sources

Antiepileptic potential of ganaxolone [PDF]

open access: yesVojnosanitetski Pregled, 2017
nema
Janković Slobodan, Lukić Snežana
doaj   +1 more source

Plastic reorganisation of human motor cortex [PDF]

open access: yesVojnosanitetski Pregled, 2012
nema
Ilić Tihomir V., Ilić Nela V.
doaj   +1 more source

Reviewing the mechanism of propofol addiction

open access: yesAll Life, 2023
Propofol is widely used as a short-acting intravenous anaesthetic for the induction and maintenance of anaesthetic sedation. The application of propofol is expanding due to its advantages and the increasing demand for painless diagnosis and treatment ...
Tianhao Zhong   +5 more
doaj   +1 more source

High concentration of dopamine treatment may induce acceleration of human sperm motility

open access: yesReproductive Medicine and Biology, 2022
Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno   +5 more
doaj   +1 more source

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