Results 261 to 270 of about 165,229 (327)

CENTRAL NEUROTRANSMITTERS AND ANAESTHETIC AGENTS

open access: closedProceedings of the Association of Veterinary Anaesthetists, 1980
David Lodge
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Chemotherapeutic agents do not interact with neurotransmitter receptors

open access: closedCancer Chemotherapy and Pharmacology, 1987
The interactions of cisplatin, 5-fluorouracil, doxorubicin, mitomycin, carmustine (BCNU), cyclophosphamide, methotrexate and thio-TEPA were assessed at three neurotransmitter receptor binding sites. Each drug was inactive at concentrations as high as 10(-4) M in displacing the specific binding of 3H-spiperone to dopamine D2, 3H-pyrilamine to histamine ...
StephenJ. Peroutka
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Discoveries of Neurotransmitter Agents and Modulators of Neuronal Functions

open access: closed, 1992
At a dinner speech in Atlantic City in 1950, Otto Loewi commented on some facets of his work that had led to the discovery of neurochemical transmission. He mentioned that Sir Walter Fletcher, years after the discovery, reminded him that as far back as 1903 Loewi had pointed out to him the possibility of a neurochemical transmission.
Ulf von Euler
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Effects of Neurotransmitters and Neuropharmacological Agents on Phospholipid Metabolism in the Rabbit Iris Muscle

open access: closed, 1976
Since the original discovery of Hokin and Hokin1 that the application of acetyIcholine in the presence of eserine to cerebral cortex slices of guinea pigs greatly stimulated their incorporation of 32pi into certain phospholipids, which were later shown to be chiefly Phla and PhA, several investigators have confirmed this observation in a wide variety ...
Ata A. Abdel‐Latif
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Species variation in the cerebrovascular response to neurotransmitters and related vasoactive agents

open access: closedGeneral Pharmacology: The Vascular System, 1983
Constrictory and dilatory responses of pial arteries to various receptor stimulants and modulators were evaluated in vitro and compared in rat, rabbit, cat and man. For the constrictory response, differences were noted especially in the rabbit, which responded strongly to histamine but poorly to noradrenaline and prostaglandin F2 alpha. Histamine was a
Jan Erik Hardebo, John Hanko, Ch. Owman
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Effect of various depolarizing agents on endogenous amino acid neurotransmitter release in rat cortical neurons in culture

open access: closedNeurochemistry International, 1998
The purpose of this study is to determine whether differences in membrane potential and/or intracellular Ca2+ increments are implicated in a programmed release of amino acid neurotransmitters (aspartate, glutamate, glycine and GABA) in cortical neurons in culture.
Miguel Herrero   +4 more
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COMPARISON OF THE EFFECTS OF DEPOLARIZING AGENTS AND NEUROTRANSMITTERS ON REGIONAL CNS CYCLIC GMP LEVELS IN VARIOUS'ANIMALS

open access: closedJournal of Neurochemistry, 1976
Abstract— The effects of 121 mm‐K+, 10 mm‐glutamate, 5 mm‐GABA, 1 mm‐glycine, 0.1 mm‐NE, and 1–10 μmACh on cyclic GMP levels in tissue slices prepared from cerebral cortex and cerebellum of mouse, rabbit, guinea‐pig, cat, and rat were studied. Basal levels of cyclic GMP in the cerebella of mice, guinea‐pigs and cats were 4–15 and 70 pmol/mg prot in rat,
Dorothy A. Kinscherf   +4 more
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