Results 21 to 30 of about 165,229 (327)

Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons [PDF]

open access: greenExperimental Neurology, 2016
Peripheral neuropathy is a dose-limiting side effect of anticancer treatment with the microtubule-targeted agents (MTAs), paclitaxel and epothilone B (EpoB); however, the mechanisms by which the MTAs alter neuronal function and morphology are unknown. We previously demonstrated that paclitaxel alters neuronal sensitivity, in vitro, in the presence of ...
Sherry K. Pittman   +2 more
openalex   +4 more sources

Effects of Z-338, a novel gastroprokinetic agent, on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema

open access: diamondJournal of Smooth Muscle Research, 2010
We investigated the effects of the novel gastroprokinetic agent Z-338 on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema (AP). Iontophoretic applications of acetylcholine (ACh), AMPA and NMDA increased, while GABA suppressed the firing rates of AP neurons recorded by extracellular electrodes.
Hironari Akaike   +5 more
openalex   +5 more sources

Antiepileptic potential of ganaxolone [PDF]

open access: yesVojnosanitetski Pregled, 2017
nema
Janković Slobodan, Lukić Snežana
doaj   +1 more source

Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters

open access: hybridBiochemical and Biophysical Research Communications, 1990
The polypeptides PDGF, TGF alpha, and EGF have previously been shown by others to stimulate proliferation of fibroblasts and keratinocytes in the process of wound healing. Here we demonstrate that extracellular ATP, ADP or AMPPNP caused synergistic enhancement of DNA synthesis in 3T6 mouse fibroblasts and BALB/MK keratinocytes when combined with any of
Dingji Wang   +2 more
openalex   +4 more sources

Plastic reorganisation of human motor cortex [PDF]

open access: yesVojnosanitetski Pregled, 2012
nema
Ilić Tihomir V., Ilić Nela V.
doaj   +1 more source

Reviewing the mechanism of propofol addiction

open access: yesAll Life, 2023
Propofol is widely used as a short-acting intravenous anaesthetic for the induction and maintenance of anaesthetic sedation. The application of propofol is expanding due to its advantages and the increasing demand for painless diagnosis and treatment ...
Tianhao Zhong   +5 more
doaj   +1 more source

Effects of various amino acids and their related agents in association with neurotransmitter substances on the morphine-induced Straub tail reaction in mice.

open access: bronzeChemical and Pharmaceutical Bulletin, 1978
Experiments were carried out in an attempt to elucidate the effects of various amino acids and their related agents in association with neurotransmitter substances on the morphine-induced Straub tail reaction (STR) in mice, using intracerebral injection technique.
Tsutomu Kameyama   +2 more
openalex   +5 more sources

High concentration of dopamine treatment may induce acceleration of human sperm motility

open access: yesReproductive Medicine and Biology, 2022
Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno   +5 more
doaj   +1 more source

Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients

open access: yesMedicina, 2020
Delirium, an acute alteration in mental status characterized by confusion, inattention and a fluctuating level of arousal, is a common problem in critically ill patients. Delirium prolongs hospital stay and is associated with higher mortality.
Wojciech Dabrowski   +8 more
doaj   +1 more source

Neuropharmacologic modulation of the melatonergic system

open access: yesExploration of Neuroscience, 2023
The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating the internal clock of the body.
Utku Aykan   +3 more
doaj   +1 more source

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