Results 21 to 30 of about 3,321,798 (216)

Plastic reorganisation of human motor cortex [PDF]

open access: yesVojnosanitetski Pregled, 2012
nema
Ilić Tihomir V., Ilić Nela V.
doaj   +1 more source

High concentration of dopamine treatment may induce acceleration of human sperm motility

open access: yesReproductive Medicine and Biology, 2022
Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno   +5 more
doaj   +1 more source

Neuropharmacologic modulation of the melatonergic system

open access: yesExploration of Neuroscience, 2023
The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating the internal clock of the body.
Utku Aykan   +3 more
doaj   +1 more source

Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease

open access: yesMolecules, 2020
Memantine (3,5-dimethyladamantan-1-amine) is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist approved for treatment of moderate-to-severe Alzheimer’s disease (AD), a neurodegenerative condition characterized by a ...
G. Marotta   +3 more
semanticscholar   +1 more source

Counteracting Poisoning with Chemical Warfare Nerve Agents

open access: yesArhiv za Higijenu Rada i Toksikologiju, 2020
Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of ...
N. M. Hrvat, Z. Kovarik
semanticscholar   +1 more source

Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients

open access: yesMedicina, 2020
Delirium, an acute alteration in mental status characterized by confusion, inattention and a fluctuating level of arousal, is a common problem in critically ill patients. Delirium prolongs hospital stay and is associated with higher mortality.
Wojciech Dabrowski   +8 more
doaj   +1 more source

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins

open access: yesFrontiers in Neuroscience, 2017
Molecular changes associated with neuronal aging lead to a decrease in cognitive capacity. Here we discuss these alterations at the level of brain regions, brain cells, and brain membrane and cytoskeletal proteins with an special focus in NMDA molecular ...
Jesús Avila   +13 more
doaj   +1 more source

Disminución del número de neuronas que expresan GABA en la corteza cerebral de ratones infectados con rabia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Algunos signos clínicos de la rabia y estudios experimentales previos sugieren que esta infección viral podría afectar al sistema GABAérgico. Objetivo. Evaluar el efecto de la infección con el virus de la rabia sobre la expresión de GABA en
Aura Caterine Rengifo   +1 more
doaj   +1 more source

Neurotransmitter-responsive nanosensors for T2-weighted magnetic resonance imaging.

open access: yesJournal of the American Chemical Society, 2019
Neurotransmitter-sensitive contrast agents for magnetic resonance imaging (MRI) have recently been used for mapping signaling dynamics in live animal brains, but paramagnetic sensors for T1-weighted MRI are usually effective only at micromolar ...
Vivian L. Hsieh   +9 more
semanticscholar   +1 more source

Robot technology identifies a Parkinsonian therapeutics repurpose to target stem cells of glioblastoma

open access: yesCNS Oncology, 2020
Aim: Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need.
Andres Vargas-Toscano   +10 more
doaj   +1 more source

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