Results 21 to 30 of about 156,401 (247)
Neurotransmitter Specific, Cellular-Resolution Functional Brain Mapping Using Receptor Coated Nanoparticles: Assessment of the Possibility. [PDF]
, 2015 Receptor coated resonant nanoparticles and quantum dots are proposed to provide a cellular-level resolution image of neural activities inside the brain. The functionalized nanoparticles and quantum dots in this approach will selectively bind to different
Forati, Ebrahim +5 more
core +6 more sources
Neuropharmacologic modulation of the melatonergic system
Exploration of Neuroscience, 2023 The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating the internal clock of the body.
Utku Aykan +3 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2007 Introducción. Algunos signos clínicos de la rabia y estudios experimentales previos sugieren que esta infección viral podría afectar al sistema GABAérgico. Objetivo. Evaluar el efecto de la infección con el virus de la rabia sobre la expresión de GABA en
Aura Caterine Rengifo +1 more
doaj +1 more source
Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients
Medicina, 2020 Delirium, an acute alteration in mental status characterized by confusion, inattention and a fluctuating level of arousal, is a common problem in critically ill patients. Delirium prolongs hospital stay and is associated with higher mortality.
Wojciech Dabrowski +8 more
doaj +1 more source
Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. [PDF]
, 2014 Small molecules that increase the presynaptic function of aminergic cells may provide neuroprotection in Parkinson's disease (PD) as well as treatments for attention deficit hyperactivity disorder (ADHD) and depression.
Biedermann, T +13 more
core +2 more sources
Frontiers in Neuroscience, 2017 Molecular changes associated with neuronal aging lead to a decrease in cognitive capacity. Here we discuss these alterations at the level of brain regions, brain cells, and brain membrane and cytoskeletal proteins with an special focus in NMDA molecular ...
Jesús Avila +13 more
doaj +1 more source
Synaptic polarity and sign-balance prediction using gene expression data in the Caenorhabditis elegans chemical synapse neuronal connectome network [PDF]
PLOS Computational Biology, 2020, 16(12): e1007974, 2021 Graph theoretical analyses of nervous systems usually omit the aspect of connection polarity, due to data insufficiency. The chemical synapse network of Caenorhabditis elegans is a well-reconstructed directed network, but the signs of its connections are yet to be elucidated.
arxiv +1 more source
Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]
, 2017 The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core +3 more sources
CNS Oncology, 2020 Aim: Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need.
Andres Vargas-Toscano +10 more
doaj +1 more source
Amperometric Measurements and Dynamic Models Reveal a Mechanism for How Zinc Alters Neurotransmitter Release [PDF]
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020,
59 (8), pp.3083-3087, 2020 Zinc, a suspected potentiator of learning and memory, is shown to affect exocytotic release and storage in neurotransmitter-containing vesicles. Structural and size analysis of the vesicular dense core and halo using transmission electron microscopy was combined with single-cell amperometry to study the vesicle size changes induced after zinc treatment
arxiv +1 more source