Results 51 to 60 of about 156,401 (247)

Smart Contrast Agents for Magnetic Resonance Imaging

open access: yesCHIMIA, 2016
By visualizing bioactive molecules or biological parameters in vivo, molecular imaging is searching for information at the molecular level in living organisms.
Célia S. Bonnet, Éva Tóth
doaj   +1 more source

Nitric oxide and synaptic function [PDF]

open access: yes, 1994
The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core   +1 more source

Current Advances in Allosteric Modulation of Muscarinic Receptors

open access: yesBiomolecules, 2020
Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter.
Jan Jakubik, Esam E. El-Fakahany
doaj   +1 more source

ADMET and Druglikeness Calculations of Sarin, Soman, and Their Hypothetical Derivatives

open access: yesIraqi Journal of Industrial Research, 2022
Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) represents a numerical classification of any chemical to be a drug candidate with promising therapeutic efficacy with minimum toxicity or sensitivity depending on its chemical ...
Kafa Khalaf Hammud
doaj   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

open access: yes, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons [PDF]

open access: yes, 1974
The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
Chun, Linda L. Y., Patterson, Paul H.
core   +1 more source

Learning as Reinforcement: Applying Principles of Neuroscience for More General Reinforcement Learning Agents [PDF]

open access: yesarXiv, 2020
A significant challenge in developing AI that can generalize well is designing agents that learn about their world without being told what to learn, and apply that learning to challenges with sparse rewards. Moreover, most traditional reinforcement learning approaches explicitly separate learning and decision making in a way that does not correspond to
arxiv  

The enteric nervous system : new developments and emerging concepts [PDF]

open access: yes, 2011
The enteric nervous system (ENS) is an integrative neuronal network, organized in two ganglionated plexuses, myenteric and submucosal, composed of neurons and enteric glial cells, controlling the activity of the smooth muscle of the gut, mucosal ...
Garzia Zizzo, Maria   +2 more
core   +2 more sources

Treatment of Erectile Dysfunction: Update

open access: yesAmerican Journal of Men's Health, 2007
Erectile dysfunction (ED) is the inability to achieve and maintain an erection. Erectile function is dependent upon complex interactions of neural and vascular pathways.
Rupesh Raina   +3 more
doaj   +1 more source

Synthesis and Biological Evaluation of O6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases

open access: yesAntioxidants, 2023
Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels.
Ahmed H. E. Hassan   +14 more
doaj   +1 more source

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