Results 21 to 30 of about 169,266 (282)

A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs)

Frontiers in Pharmacology, 2016
This perspective was adapted from a Career Achievement Award talk given at the International Cannabinoid Research Society Symposium in Bukovina, Poland on June 27, 2016.
Dale Deutsch
doaj   +1 more source

The Anti-Inflammatory Effects of Blueberries in an Animal Model of Post-Traumatic Stress Disorder (PTSD).

PLoS ONE, 2016
Post-traumatic stress disorder (PTSD) is a trauma and stressor-related disorder that results in a prolonged stress response. It is associated with increased oxidative stress and inflammation in the prefrontal cortex (PFC) and hippocampus (HC).
Philip J Ebenezer, C Brad Wilson, Leslie D Wilson, Anand R Nair, Francis J   +4 more
doaj   +1 more source

Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]

, 1990
A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D, Suidan, H S, Tolkovsky, A M, Walker, A E   +3 more
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Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters

Nature Communications, 2020
Norepinephrine is a biogenic amine neurotransmitter that has widespread effects on alertness, arousal and pain sensation. Consequently, blockers of norepinephrine uptake have served as vital tools to treat depression and chronic pain. Here, we employ the
Shabareesh Pidathala, A. K. Mallela, D. Joseph, A. Penmatsa   +3 more
semanticscholar   +1 more source

Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway

Cell Communication and Signaling, 2018
Background Besides its neurotransmitter and vasoconstriction functions, serotonin is an important mediator of numerous biological processes in peripheral tissues including cell proliferation, steatosis, and fibrogenesis.
Suryakant Niture, Maxwell A. Gyamfi, Habib Kedir, Elena Arthur, Habtom Ressom, Gagan Deep, Deepak Kumar   +6 more
doaj   +1 more source

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton, Cheng-Fang Hsieh, Gillian E Mead, Graeme J Hankey, Mansur A Kutlubaev, Maree L Hackett, Rebecca Lee   +6 more
core   +1 more source

Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]

, 2020
Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F, Busceti, CL, Fabrizi, C, Fornai, F, Limanaqi, F, Polzella, M   +5 more
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Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo. [PDF]

, 2013
In this study, we characterized early biochemical changes associated with sertraline and placebo administration and changes associated with a reduction in depressive symptoms in patients with major depressive disorder (MDD).
Bogdanov, MB, Boyle, SH, Churchill, E, Delnomdedieu, M, Fiehn, O, Kaddurah-Daouk, R, Krishnan, RR, Pickering, E, Rush, AJ, Wang, Z, Wikoff, WR, Zhu, H   +11 more
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The kynurenine pathway and the brain: challenges, controversies and promises [PDF]

, 2017
Research on the neurobiology of the kynurenine pathway has suffered years of relative obscurity because tryptophan degradation, and its involvement in both physiology and major brain diseases, was viewed almost exclusively through the lens of the well ...
Schwarcz, Robert, Stone, Trevor W.
core   +1 more source

Inactivation of anandamide signaling : A continuing Debate [PDF]

, 2010
Copyright 2011 Elsevier B.V., All rights reserved.Peer reviewedPublisher ...
Ahluwalia, Ahn, Alexander, Alexander, Beltramo, Bhave, Bifulco, Bisogno, Bisogno, Bosier, Cadas, Chen, Chuang, Clapper, Cravatt, Cravatt, Cristino, Day, De Petrocellis, De Petrocellis, De Petrocellis, Desarnaud, Deutsch, Deutsch, Devane, Devane, Di Carlo, Di Marzo, Di Marzo, Di Marzo, Egertova, Evans, Evans, Evans, Fedorova, Glaser, Guzmán, Hampson, Hanus, Harizi, Hesham Khairy, Hillard, Hillard, Hillard, Horvath, Howlett, Howlett, Iversen, Jarrahian, Jiang, Jonsson, Kaczocha, Kaczocha, Katayama, Kathuria, Khairy, Klein, Koutek, Kulkarni-Narla, Liu, Long, Maccarrone, Malcher-Lopes, Matsuda, McFarland, Mechoulam, Mechoulam, Mechoulam, Mechoulam, Miller, Moore, Mulder, Munro, Numazaki, Okamoto, Ortar, Pertwee, Piomelli, Poling, Porter, Premkumar, Randall, Schlosburg, Schmid, Simon, Stella, Stremmel, Sun, Sun, Sánchez, Thomas, Thors, Tian, Tsou, Tsuboi, Ueda, Ueda, Van den Bossche, Van Der Stelt, Wael E. Houssen, Walker, Weber, Wenger, Wood, Woodward, Yu, Zygmunt   +106 more
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