Results 11 to 20 of about 281,069 (321)

The therapeutic potential of ultra-short-acting β-receptor antagonists in perioperative analgesic: Evidence from preclinical and clinical studies

Frontiers in Pharmacology, 2022
Perioperative multimodal analgesia can reduce the side effects of a high concentration of opioids, improving the comfort of the patient. However, insufficient analgesia of this model has prompted researchers to explore new adjuvant analgesics.
Linbin Fu, Buwei Yu, Zheng Li, Zhiheng Liu   +3 more
doaj   +1 more source

Data and calculus on isobolographic analysis to determine the antinociceptive interaction between calcium channel blocker and a TRPV1 blocker in acute pain model in mice

Data in Brief, 2017
Determining antinociceptive interaction between Phα1β toxin (a voltage gated calcium channel blocker) and SB366791 (selective TRPV1 antagonist) may have both clinical and mechanistic implications for the pain management.
Juliana F. Silva, Manuella R. Palhares, Duana C. Santos, Cláudio A. Silva-Junior, Juliano Ferreira, Marcus V. Gomez, Célio J. Castro Junior   +6 more
doaj   +1 more source

Beyond Cholinesterase Inhibition. Anti-Inflammatory Role and Pharmacological Profile of Current Drug Therapy for Alzheimer's Disease [PDF]

, 2016
Inflammation is a common response of an individual against either exogenous or endogenous damage. The role of inflammation and of inflammatory cells recently emerged also in the pathogenesis of neurodegenerative disorders. Experimental evidences show how
GIUBILEI, Franco
core   +1 more source

The Effect of Renal Denervation on Plasma Adipokine Profile in Patients with Treatment Resistant Hypertension

Frontiers in Physiology, 2017
Background: We previously demonstrated the effectiveness of renal denervation (RDN) to lower blood pressure (BP) at least partially via the reduction of sympathetic stimulation to the kidney.
Nina Eikelis, Nina Eikelis, Dagmara Hering, Dagmara Hering, Petra Marusic, Petra Marusic, Jacqueline Duval, Louise J. Hammond, Antony S. Walton, Elisabeth A. Lambert, Elisabeth A. Lambert, Murray D. Esler, Murray D. Esler, Gavin W. Lambert, Gavin W. Lambert, Markus P. Schlaich, Markus P. Schlaich, Markus P. Schlaich   +17 more
doaj   +1 more source

Android Fat Deposition and Its Association With Cardiovascular Risk Factors in Overweight Young Males

Frontiers in Physiology, 2019
ObjectiveExcess adiposity increases the risk of type-2 diabetes and cardiovascular disease development. Beyond the simple level of adiposity, the pattern of fat distribution may influence these risks.
Carolina Ika Sari, Nina Eikelis, Nina Eikelis, Geoffrey A. Head, Markus Schlaich, Peter Meikle, Gavin Lambert, Gavin Lambert, Elisabeth Lambert, Elisabeth Lambert   +9 more
doaj   +1 more source

Norepinephrine transporter expression is inversely associated with glycaemic indices: a pilot study in metabolically diverse persons with overweight and obesity

Obesity Science & Practice, 2016
Summary Objective The objective of this study was to examine the cross‐sectional relationship between the expression of norepinephrine transporter (NET), the protein responsible for neuronal uptake‐1, and indices of glycaemia and hyperinsulinaemia, in ...
N. E. Straznicky, L. Guo, S. J. Corcoran, M. D. Esler, S. E. Phillips, C. I. Sari, M. T. Grima, S. Karapanagiotidis, C. Y. Wong, N. Eikelis, J. A. Mariani, D. Kobayashi, J. B. Dixon, G. W. Lambert, E. A. Lambert   +14 more
doaj   +1 more source

Endothelial Function in Healthy Young Individuals Is Associated with Dietary Consumption of Saturated Fat

Frontiers in Physiology, 2017
Background: A diet rich in fat, in particular saturated fat (SF), may be linked to cardiovascular disease development, possibly due to a detrimental effect of fat on endothelial function (EF).Objective: We aimed to determine whether the habitual SF ...
Elisabeth A. Lambert, Elisabeth A. Lambert, Sarah Phillips, Sarah Phillips, Regina Belski, Ainura Tursunalieva, Nina Eikelis, Nina Eikelis, Carolina I. Sari, John B. Dixon, John B. Dixon, John B. Dixon, John B. Dixon, Nora Straznicky, Mariee Grima, Geoffrey A. Head, Markus Schlaich, Gavin W. Lambert, Gavin W. Lambert   +18 more
doaj   +1 more source

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. [PDF]

, 2020
Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones.
Biglia, Nicoletta, Birkhaeuser, Martin, Brincat, Mark, Celis-Gonzales, Cuauhtémoc, Depypere, Herman, Egarter, Christian, Fait, Tomas, Genazzani, Andrea, Goldstein, Steven, Mueck, Alfred, Palacios, Santiago, Panay, Nick, Ruan, Xiangyan, Simoncini, Tommaso, Skouby, Sven O   +14 more
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Effects of Different Ammonia Concentrations on Pulmonary Microbial Flora, Lung Tissue Mucosal Morphology, Inflammatory Cytokines, and Neurotransmitters of Broilers

Animals, 2022
Atmospheric ammonia is one of the main environmental stressors affecting the performance of broilers. Previous studies demonstrated that high levels of ammonia altered pulmonary microbiota and induced inflammation.
Guangju Wang, Qingxiu Liu, Ying Zhou, Jinghai Feng, Minhong Zhang   +4 more
doaj   +1 more source

Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]

, 1983
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor, Bennett, Cervero, Cervero, Cervero, Cervero, Coggeshall, Coggeshall, Dhanjal, Dhanjal, Dubuisson, Fry, Hentall, Hunt, Hökfelt, Kumazawa, Kumazawa, Light, Miletic, Murase, Price, Ruda, Sumal, W. Zieglgänsberger, Wall, Wall, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +29 more
core   +1 more source