Results 11 to 20 of about 124,933 (262)

Depression, Neuroplasticity and Neurotrophic Factors [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2009
Depression is a common psychiatric disorder. There is still very little known about the neurobiological alterations that underlie the pathophysiology of depression.
Cengiz Akkaya   +3 more
doaj   +1 more source

Neurotrophic factors and corneal nerve regeneration [PDF]

open access: yesNeural Regeneration Research, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Marta Sacchetti, Alessandro Lambiase
doaj   +2 more sources

MANF: A New Player in the Control of Energy Homeostasis, and Beyond

open access: yesFrontiers in Physiology, 2018
All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
doaj   +1 more source

The Role of BDNF on Neural Plasticity in Depression

open access: yesFrontiers in Cellular Neuroscience, 2020
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that depression is closely related to the abnormal neural plasticity processes occurring in the prefrontal cortex and limbic system such as the hippocampus and amygdala ...
Tao Yang   +7 more
doaj   +1 more source

Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells. [PDF]

open access: yesPLoS ONE, 2011
Recent studies have indicated that the choice of lineage of neural progenitor cells is determined, at least in part, by environmental factors, such as neurotrophic factors.
Masaya Nakamura   +4 more
doaj   +1 more source

Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system [PDF]

open access: yes, 2007
Support of ageing neurons by endogenous neurotrophic factors such as glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may determine whether the neurons resist or succumb to neurodegeneration.
Aron, Liviu   +27 more
core   +1 more source

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

open access: yesNeural Regeneration Research, 2017
Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio   +3 more
doaj   +1 more source

Collagen scaffold loaded allogeneic neural stem cells promoted locomotion recovery of spinal cord injury mainly through secreting neurotrophic factors

open access: yesMaterials & Design, 2022
The combination of biological scaffold and neural stem cells (NSCs) is a promising treatment strategy for spinal cord injury (SCI). But adverse niche at injures spinal cord severe hamper the transplanted NSCs to preferentially differentiate neurons.
Shuo Liu   +5 more
doaj   +1 more source

Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease

open access: yesLife, 2023
The involvement of the changed expression/function of neurotrophic factors in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD), has been suggested.
Tadahiro Numakawa, Ryutaro Kajihara
doaj   +1 more source

Peripheral blood neurotrophic factor levels in children with autism spectrum disorder: a meta-analysis

open access: yesScientific Reports, 2021
Increasing evidence suggests that abnormal regulation of neurotrophic factors is involved in the etiology and pathogenesis of Autism Spectrum Disorder (ASD).
Shu-Han Liu   +3 more
doaj   +1 more source

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