Results 21 to 30 of about 185,165 (275)

Involvement of ras p2I in Neurotrophin-induced Response of Sensory, but Not Sympathetic Neurons [PDF]

open access: yes, 1993
Little is known about the signal transduction mechanisms involved in the response to neurotrophins and other neurotrophic factors in neurons, beyond the activation of the tyrosine kinase activity of the neurotrophin receptors belonging to the trk family.
Barde, Y. A.   +4 more
core   +3 more sources

Peripheral blood neurotrophic factor levels in children with autism spectrum disorder: a meta-analysis

open access: yesScientific Reports, 2021
Increasing evidence suggests that abnormal regulation of neurotrophic factors is involved in the etiology and pathogenesis of Autism Spectrum Disorder (ASD).
Shu-Han Liu   +3 more
doaj   +1 more source

Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]

open access: yes, 2020
Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F   +5 more
core   +2 more sources

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

open access: yesNeural Regeneration Research, 2017
Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio   +3 more
doaj   +1 more source

Collagen scaffold loaded allogeneic neural stem cells promoted locomotion recovery of spinal cord injury mainly through secreting neurotrophic factors

open access: yesMaterials & Design, 2022
The combination of biological scaffold and neural stem cells (NSCs) is a promising treatment strategy for spinal cord injury (SCI). But adverse niche at injures spinal cord severe hamper the transplanted NSCs to preferentially differentiate neurons.
Shuo Liu   +5 more
doaj   +1 more source

Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease

open access: yesLife, 2023
The involvement of the changed expression/function of neurotrophic factors in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD), has been suggested.
Tadahiro Numakawa, Ryutaro Kajihara
doaj   +1 more source

Safety and feasibility of Lin- cells administration to ALS patients : a novel view on humoral factors and miRNA profiles [PDF]

open access: yes, 2018
Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular
Baumert, Bartłomiej   +12 more
core   +2 more sources

Neurotrophic factor-based pharmacological approaches in neurological disorders

open access: yesNeural Regeneration Research, 2023
Aging is a physiological event dependent on multiple pathways that are linked to lifespan and processes leading to cognitive decline. This process represents the major risk factor for aging-related diseases such as Alzheimer’s disease, Parkinson’s ...
Margherita Alfonsetti   +2 more
doaj   +1 more source

Neurotrophic factors in tension-type headache

open access: yesArquivos de Neuro-Psiquiatria, 2015
Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH).
Renan B. Domingues   +3 more
doaj   +1 more source

Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research

open access: yesNeural Plasticity, 2022
Ischemic stroke and traumatic brain injury (TBI) are among the leading causes of death and disability worldwide with impairments ranging from mild to severe.
Serena-Kaye Sims   +5 more
doaj   +1 more source

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