Results 51 to 60 of about 7,894,191 (193)

Peripheral biomarkers in bipolar disorder manic episode

open access: yesPsychiatry and Behavioral Sciences, 2017
Bipolar disorder is a chronic illness of which the etiology is not fully elucidated. Recently, in order to understand the pathophysiogy of bipolar disorder, oxidative stress, inflammation, and neurotrophic factors have been widely studied. Although there
Abdullah Genc   +2 more
doaj   +1 more source

ELISA‐based quantification of neurotrophic growth factors in urine from prostate cancer patients

open access: yesFASEB BioAdvances, 2021
Non‐invasive procedures are needed for prostate cancer management, and urine represents a potential source of new biomarkers with translational value. Recent evidence has shown that the growth of new nerves in the tumor microenvironment is essential to ...
Brayden March   +5 more
doaj   +1 more source

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. [PDF]

open access: yes, 2013
Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington"s disease.
Toro Ruiz, Daniel del   +5 more
core   +1 more source

Effect of selegiline on neural stem cells differentiation: a possible role for neurotrophic factors [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s): The stimulation of neural stem cells (NSCs) differentiation into neurons has attracted great attention in management of neurodegenerative disease and traumatic brain injury. It has been reported that selegiline could enhance the morphologic
Kambiz Hassanzadeh   +3 more
doaj  

Alzheimer’s Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound

open access: yesBiomolecules, 2022
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with an insidious onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are considered the early pathological features associated with neurofibrillary tau ...
Narjes Baazaoui, Khalid Iqbal
doaj   +1 more source

Neurotrophic Factors and Their Potential Applications in Tissue Regeneration

open access: yes, 2016
Neurotrophic factors are growth factors that can nourish neurons and promote neuron survival and regeneration. They have been studied as potential drug candidates for treating neurodegenerative diseases.
Xiao, Nan (Tori), Le, Quynh-Thu
core   +1 more source

EFFECT OF GLYPROLINES ON THE LEVEL OF APOPTOTIC AND NEUROTROPHIC FACTORS UNDER CONDITIONS OF “SOCIAL” STRESS

open access: yesФармация и фармакология (Пятигорск), 2021
The aim of the article was to study the effect of glyproline neuropeptide compounds Thr–Lys–Pro–Arg–Pro–Gly–Pro (Selank), Pro–Gly–Pro and Pro–Gly–Pro–Leu, on the level of apoptotic factors (caspase-3, caspase-8, the tumor necrosis factor) and ...
A. L. Yasenyavskaya   +5 more
doaj   +1 more source

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)

open access: yesNeurobiology of Disease, 2013
This paper reassesses the currently accepted viewpoint that targeting the terminal fields (i.e. striatum) of degenerating nigrostriatal dopamine neurons with neurotrophic factors in Parkinson's disease (PD) is sufficient for achieving an optimal ...
Christopher D. Herzog   +7 more
doaj   +1 more source

Cross‐talk between motor neurons and myotubes via endogenously secreted neural and muscular growth factors

open access: yesPhysiological Reports, 2021
Neuromuscular junction (NMJ) research is vital to advance the understanding of neuromuscular patho‐physiology and development of novel therapies for diseases associated with NM dysfunction.
Jasdeep Saini   +8 more
doaj   +1 more source

Neurotrophic factors and neuropathic pain

open access: yes, 2001
Neuropathic pain is a debilitating consequence of nerve damage. Existing treatment is largely ineffective. Current models of neuropathic pain recognise the importance of ectopic activity in primary sensory neurones impinging on a sensitised central ...
Boucher, T J, McMahon, S B, T Boucher
core   +1 more source

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