Results 51 to 60 of about 124,933 (262)

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)

Neurobiology of Disease, 2013
This paper reassesses the currently accepted viewpoint that targeting the terminal fields (i.e. striatum) of degenerating nigrostriatal dopamine neurons with neurotrophic factors in Parkinson's disease (PD) is sufficient for achieving an optimal ...
Christopher D. Herzog, Lamar Brown, Brian R. Kruegel, Alistair Wilson, Malú G. Tansey, Fred H. Gage, Eugene M. Johnson, Jr., Raymond T. Bartus   +7 more
doaj   +1 more source

Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains [PDF]

, 2009
Several lines of evidence implicate BDNF in the pathophysiology of psychiatric illness. BDNF polymorphisms have also been associated with the risk of schizophrenia and mood disorders.
Dunham, Jason S., Deakin, J. F W; id_orcid, Payton, A., Miyajima, F., Deakin, J. F. William, Toro, Carla T., Toro, Carla Tatiana, Dunham, J. S., Payton, Tony, Miyajima, Fabio, Toro, C. T., Payton, A.; id_orcid, Deakin, J. F. W.   +12 more
core   +1 more source

AMSCs secreted neurotrophic factors in vitro.

, 2022
The ability of AMSCs to secrete trophic factors was evaluated using ELISA. Neurotrophic factors such as (A) BDNF, (B) VEGF, and (C) b-FGF were significantly secreted from AMSCs compared with the control medium.
Sho Yamaguchi (5309186), Shunsuke Ohnishi (167269), Masahito Kawabori (13021466), Kazuyoshi Yamazaki (7387250), Toshitaka Seki (13021472), Kotaro Konno (534026), Khin Khin Tha (13021475), Miki Fujimura (7244756), Koji Yamamoto (505190), Soichiro Takamiya (13021463), Kiyohiro Houkin (562861), Aki Tanimori (13021469), Daigo Hashimoto (13021478), Masahiko Watanabe (47746)   +13 more
core   +1 more source

Developing a Functional Polyelectrolyte Hybrid Layer Scaffold Coating and Evaluation of Its Performance for Interaction With Neural Cells

Advanced Materials Interfaces, EarlyView.
Polyelectrolyte scaffold coatings modified with Cu and Fe3O4 nanoparticles regulate neural stem cell behavior in vitro. Increased Fe3O4 content enhances mitochondrial activity and neuronal differentiation, whereas higher Cu levels reduce cell viability.
Anna Grzeczkowicz, Agata Lipko, Angelika Kwiatkowska, Marcin Strawski, Monika Drabik, Ludomira H. Granicka   +5 more
wiley   +1 more source

Hippocampal neurogenesis and antidepressive therapy: shocking relations. [PDF]

, 2014
Speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago.
Aigner, Ludwig, Ludwig Aigner, Lange, Simona, Marschallinger, Julia, O’Sullivan, Anna, Zaunmair, Pia, Couillard-Despres, Sebastien, Simona Lange, Sebastien Couillard-Despres, Christian Geretsegger, Anna O’Sullivan, Pia Zaunmair, Peter Rotheneichner, Rotheneichner, Peter, Geretsegger, Christian, Julia Marschallinger   +15 more
core   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Preclinical Testing of Neuroprotective Neurotrophic Factors in a Model of Chronic Motor Neuron Degeneration

Neurobiology of Disease, 1999
Many neurotrophic factors have been shown to enhance survival of embryonic motor neurons or affect their response to injury. Few studies have investigated the potential effects of neurotrophic factors on more mature motor neurons that might be relevant ...
Andrea M. Corse, Masako M. Bilak, Stephan R. Bilak, Mohamed Lehar, Jeffrey D. Rothstein, Ralph W. Kuncl   +5 more
doaj   +1 more source

Enteric nervous system: Neurotrophic factors

, 2009
The enteric nervous system (ENS) is the most complex region of the peripheral nervous system. The roles of neurotrophic factors in the early development of the ENS are relatively well established.
Saffrey, Jill, M.J. Saffrey
core   +1 more source