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NGF in Neuropathic Pain: Understanding Its Role and Therapeutic Opportunities [PDF]
Current Issues in Molecular BiologyNerve growth factor (NGF) is one of the essential components that have been implicated in the pathophysiology of neuropathic pain, a condition that develops following nerve injury or dysfunction.
Mario García-Domínguez
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Optimizing transport methods to preserve function of self‐innervating muscle cells for laryngeal injection [PDF]
Laryngoscope Investigative OtolaryngologyObjectives Recently, our laboratory has discovered a self‐innervating population of muscle cells, called motor endplate‐expressing cells (MEEs). The cells innately release a wide variety of neurotrophic factors into the microenvironment promoting ...
Samuel L. Kaefer +5 more
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The Molecular Effects of BDNF Synthesis on Skeletal Muscle: A Mini-Review
Frontiers in Physiology, 2022 The brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family which is generated mainly by the brain. Its main role involve synaptic modulation, neurogenesis, neuron survival, immune regulation, myocardial contraction, and ...
I. Rentería +7 more
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Frontiers in Molecular Neuroscience, 2023 Alterations in adult neurogenesis are a common hallmark of neurodegenerative diseases. Therefore, understanding the molecular mechanisms that control this process is an indispensable requirement for designing therapeutic interventions addressing ...
Anna Lozano-Ureña, José M. Frade
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Crystals of the neurotrophins [PDF]
Protein Science, 1996 AbstractThe neurotrophins show a high degree of amino acid sequence homology, share similar solution properties, and display distinct but parallel functionalities. Here we report the crystallization and preliminary X‐ray characterization of three neurotrophins: brain‐derived neurotrophin, neurotrophin 3, and the heterodimer between brain‐derived ...
Robinson, R +3 more
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Biomedicines, 2023 Oleuropein (OLE), a main constituent of olives, displays a pleiotropic beneficial dynamic in health and disease; the effects are based mainly on its antioxidant and hypolipidemic properties, and its capacity to protect the myocardium during ischemia ...
Foteini Malliou +9 more
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Fermentation, 2023 Fermentation is a widely used process in the biotechnology industry, in which sugar-based substrates are transformed into a new product through chemical reactions carried out by microorganisms.
Domenico Bonanni +10 more
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Rab10 regulates the sorting of internalised TrkB for retrograde axonal transport
eLife, 2023 Neurons process real-time information from axon terminals to coordinate gene expression, growth, and plasticity. Inputs from distal axons are encoded as a stream of endocytic organelles, termed signalling endosomes, targeted to the soma.
Oscar Marcelo Lazo, Giampietro Schiavo
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Animals, 2023 The neurotrophin beta-nerve growth factor (NGF), which is present in the semen of different mammals, elicits potent ovulatory and luteotrophic actions in llamas following systemic administration.
Gonzalo Gajardo +9 more
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Frontiers in Molecular Neuroscience, 2023 IntroductionThe potential benefits of natural ingredients in the alleviation of neurodegenerative disorders are of great interest. Alpha-pinene (APN) is an essential oil belonging to monoterpenes with multiple beneficial effects.
Paria Hashemi, Shamseddin Ahmadi
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