Results 151 to 160 of about 53,997 (300)

The structures of the neurotrophin 4 homodimer and the brain‐derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk‐binding site [PDF]

, 1999
Robert Robinson, Senyon Choe, Czeslaw Radziejewski, Glen Spraggon, Jason Greenwald, M. Kostura, Leslie D. Burtnick, David I. Stuart, E. Yvonne Jones   +8 more
openalex   +1 more source

Nerve Growth Factor Receptor (NGFR/p75NTR) of the Small‐Spotted Catshark (Scyliorhinus canicula): Evolutionary Conservation and Brain Function

Journal of Comparative Neurology, Volume 533, Issue 4, April 2025.
p75NTR expression in the brain of the basal vertebrate Scyliorhinus canicula revealed its conservation across species. Functional conservation among vertebrates was demonstrated (i) by performing the canonical PC‐12 differentiation assay with the S. canicula NGF and (ii) by complementing the p75NTR absence in a PC‐12 p75NTR−/− knock‐out clone with the ...
Elena Chiavacci, Roberta Camera, Mario Costa, Baldassare Fronte, Eva Terzibasi Tozzini, Alessandro Cellerino   +5 more
wiley   +1 more source

Drug Targets in Neurotrophin Signaling in the Central and Peripheral Nervous System

Molecular Neurobiology, 2018
M. Kashyap, Callie Roberts, M. Waseem, P. Tyagi   +3 more
semanticscholar   +1 more source

Monocyte‐Platelet Aggregates Are Major Source of BDNF after Bacterial Stimulation of Human Peripheral Blood Immune Cells

European Journal of Immunology, Volume 55, Issue 4, April 2025.
Bacterial antigens primarily induce BDNF release from platelets interacting with monocytes in PBMCs. This interplay underscores how immune‐blood cell complexes shape BDNF levels which may impact early human development. ABSTRACT The gut microbiota and the immune system are closely connected, influencing early‐life brain development.
Fabien Sarcletti, Marco Dijmarescu, Michael Eigenschink, Nadja Wukowits, Barbara Oehler, Tanja Mayer, Sarah Pell, Anastasia Tandecki, David Seki, Andreas Spittler, David Berry, Angelika Berger, Lukas Wisgrill   +12 more
wiley   +1 more source

Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons.

, 1994
Axel Leingärtner, Carl‐Philipp Heisenberg, R. Kolbeck, H. Thoenen, Dan Lindholm   +4 more
openalex   +1 more source

Neurotrophin-3 Antibodies Disrupt the Normal Development of the Chick Retina [PDF]

, 1996
Paola Bovolenta, José M. Frade, Elisa Martı́, Angeles Rodrı́guez-Peña, Yves‐Alain Barde, Alfredo Rodrı́guez-Tébar   +5 more
openalex   +1 more source

Effects of Probiotics as Adjunctive Therapy to Fluoxetine on Depression Severity and Serum Brain‐Derived Neurotrophic Factor, Cortisol, and Adrenocorticotropic Hormone in Patients With Major Depressive Disorder: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This study evaluates the impact of probiotics on depression severity and biomarkers in MDD patients. Fifty medication‐free MDD patients were randomized to receive probiotics with fluoxetine or placebo with fluoxetine for 8 weeks. Results indicated a significant reduction in depression severity in the probiotic group, though no significant differences ...
Vajihe Elahinejad, Atie Sadat Khorasanian, Mehdi Tehrani‐Doost, Kianoush Khosravi‐Darani, Zahra Mirsepasi, Mohammad Effatpanah, Reza Askari‐Rabori, Shirin Tajadod, Shima Jazayeri   +8 more
wiley   +1 more source

Modeled structure of the 75-kDa neurotrophin receptor [PDF]

, 1995
Barbara Chapman, Irwin D. Kuntz
openalex   +1 more source

Time‐restricted feeding mitigates Alzheimer's disease‐associated cognitive impairments via a B. pseudolongum‐propionic acid‐FFAR3 axis

iMeta, Volume 4, Issue 2, April 2025.
A 4‐month of time‐restricted feeding (TRF) intervention alleviated cognitive impairments in Alzheimer's disease (AD) patients, while a 3‐month TRF regimen improved spatial memory, reduced amyloid‐beta accumulation, and promoted microglial aggregation around plaques in AD mice. Antibiotic‐induced gut microbiota depletion partly abolished TRF's benefits.
Yihang Zhao, Mengzhen Jia, Chen Ding, Bingkun Bao, Hangqi Li, Jiabin Ma, Weixuan Dong, Rui Gao, Xuhui Chen, Jiao Chen, Xiaoshuang Dai, Yuanqiang Zou, Jun Hu, Lin Shi, Xuebo Liu, Zhigang Liu   +15 more
wiley   +1 more source

Adenovirus-Mediated Glial Cell Line-Derived Neurotrophic Factor (GDNF) Expression Protects against Subsequent Cortical Cold Injury in Rats

Neurobiology of Disease, 2001
We examined whether brain damage after focal cortex trauma may be attenuated by adenoviral delivery of the glial cell line-derived neurotrophic factor (GDNF) gene.
Dirk M. Hermann, Ertugrul Kilic, Sebastian Kügler, Stefan Isenmann, Mathias Bähr   +4 more
doaj