Stimulation of neurotrophin synthesis by 4-methylcatechol: a promising approach for neuroprotection
, 1999 Shoei Furukawa +2 more
openalex +2 more sources
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis +2 more
wiley +1 more source
Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction
Glia, Volume 73, Issue 12, Page 2427-2444, December 2025.Main Points When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating tor nearby glial dysfunction, glia maintain their own phagocytic Tunctions.
Allison N. Beachum +13 more
wiley +1 more source
Expression of Neurotrophin Genes in the Hypothalamus of Stressed and Allopregnanolone-Infused Sheep. [PDF]
Int J Mol SciMłotkowska P +4 more
europepmc +1 more source
Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis
Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf +3 more
wiley +1 more source
Abnormal Cerebellar Development and Foliation in BDNF−/− Mice Reveals a Role for Neurotrophins in CNS Patterning [PDF]
, 1997 Phillip M. Schwartz +4 more
openalex +1 more source
Breast Cancer Brain Metastasis: Bridging Biological Mechanisms to Therapeutic Innovations
MedComm – Oncology, Volume 4, Issue 4, December 2025.Breast cancer brain metastasis (BCBrM) is driven by a multistep metastatic cascade and shaped by dynamic tumor–brain interactions. This review integrates current mechanistic insights, from molecular signaling pathways to immune evasion, and evaluates preclinical models and emerging therapies.
Jing Feng +3 more
wiley +1 more source
Neurotrophic factors as double-edged swords in osteosarcoma: drivers of tumour growth and immune remodelling. [PDF]
Front ImmunolLei P, Li L.
europepmc +1 more source
MedComm – Oncology, Volume 4, Issue 4, December 2025.Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan +7 more
wiley +1 more source