Results 61 to 70 of about 38,974 (303)

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells

Frontiers in Immunology, 2017
Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła, Cornelia Richter, Martin Ryser, Arshad Jamal, Arshad Jamal, Michelle P. Ashton, Malte von Bonin, Malte von Bonin, Malte von Bonin, Matthias Kuhn, Benjamin Dorschner, Dimitra Alexopoulou, Katrin Navratiel, Ingo Roeder, Andreas Dahl, Christian M. Hedrich, Ezio Bonifacio, Sebastian Brenner, Sebastian Brenner, Sebastian Thieme   +19 more
doaj   +1 more source

Neurotrophins and neurotrophin receptors in pulmonary sarcoidosis - granulomas as a source of expression [PDF]

Respiratory Research, 2010
Pulmonary sarcoidosis is an inflammatory disease, characterized by an accumulation of CD4+ lymphocytes and the formation of non-caseating epithelioid cell granulomas in the lungs. The disease either resolves spontaneously or develops into a chronic disease with fibrosis.
Johan Grunewald, Caroline Olgart Höglund, Caroline Olgart Höglund, Marija Kramar, Marija Kramar, Göran Elmberger, Charlotta Dagnell, Anders Eklund, Helga Haugom-Olsen   +8 more
openaire   +4 more sources

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

The relationship between psychological distress and neurotrophins in patients with alopecia areata: A crosssectional study

Turkderm Turkish Archives of Dermatology and Venereology
Background and Design: Alopecia areata (AA) is a common, chronic, autoimmune disease that causes psychological effects on patients. Distress and psychological factors play roles in the onset and flares of the disease.
Hatice Parlak Subaşı, Hilal Kaya Erdoğan, Ersoy Acer, Evin Kocatürk, Ali Ercan Altınöz, Zeynep Nurhan Saraçoğlu, Muzaffer Bilgin   +6 more
doaj   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Endogenous neurotrophin-3 promotes neuronal sprouting from dorsal root ganglia

Neural Regeneration Research, 2015
In the present study, we investigated the role of endogenous neurotrophin-3 in nerve terminal sprouting 2 months after spinal cord dorsal root rhizotomy.
Xu-yang Wang, Pei-yuan Gu, Shi-wen Chen, Wen-wei Gao, Heng-li Tian, Xiang-he Lu, Wei-ming Zheng, Qi-chuan Zhuge, Wei-xing Hu   +8 more
doaj   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, EarlyView.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source

Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interactions, repetitive behaviors, and hyper‐ or hyposensitivity to sensory stimuli. The cellular mechanisms underlying the emergence of abnormal sensory sensitivity in ASD are not fully understood.
Alejandra Fernandez, Nick Sarn, Charis Eng, Kevin M. Wright   +3 more
wiley   +1 more source

From Neural Crest Development to Cancer and Vice Versa: How p75NTR and (Pro)neurotrophins Could Act on Cell Migration and Invasion?

Frontiers in Molecular Neuroscience, 2018
The p75 neurotrophin receptor (p75NTR), also known as low-affinity nerve growth factor, belongs to the tumor necrosis factor family of receptors. p75NTR is widely expressed in the nervous system during the development, as well as, in the neural crest ...
Sabine Wislet, Geoffrey Vandervelden, Bernard Rogister, Bernard Rogister   +3 more
doaj   +1 more source