Results 71 to 80 of about 108 (108)
Elp1 function in placode‐derived neurons is critical for proper trigeminal ganglion development
Developmental Dynamics, Volume 254, Issue 6, Page 494-512, June 2025.Abstract Background The trigeminal nerve is the largest cranial nerve and functions in somatosensation. Cell bodies of this nerve are positioned in the trigeminal ganglion, which arises from the coalescence of neural crest and placode cells. While this dual cellular origin has been known for decades, the molecular mechanisms controlling trigeminal ...
Margaret A. Hines, Lisa A. Taneyhill
wiley +1 more source
JOR SPINE, Volume 8, Issue 2, June 2025.ABSTRACT Background Intervertebral disc (IVD) degeneration (IDD) is the main contributor to chronic low back pain (LBP), the leading cause of disability worldwide, with a significant impact on the quality of life and health of common people. The etiology of IDD is still unclear, but it has been largely demonstrated the crucial role of inflammation and ...
Laura Guarnaccia +20 more
wiley +1 more source
The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases
MedComm, Volume 6, Issue 6, June 2025.Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu +7 more
wiley +1 more source
MedComm – Oncology, Volume 4, Issue 2, June 2025.Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen +11 more
wiley +1 more source
CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation
Acta Ophthalmologica, Volume 103, Issue 4, Page e240-e255, June 2025.Abstract The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular ...
Anat Galor +10 more
wiley +1 more source
International Endodontic Journal, Volume 58, Issue 6, Page 873-889, June 2025.Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.
Xiaolin Li +7 more
wiley +1 more source
Neurotrophins and their p75 receptor.
Cold Spring Harbor symposia on quantitative biology, 1996 Carter, B.D. +4 more
openaire +4 more sources
Neurotrophins and Neurotrophin Receptors in Adult Brain Plasticity
Neural Plasticity, 1992 Jonathan R. Day +7 more
openaire +2 more sources
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Autonomic Neuroscience, 2010
The aim of this review is to report recent findings and ongoing studies on the effects of acupuncture on endogenous biological mediators, in particular on neurotrophins such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Acupuncture is a therapeutic technique and is a part of Traditional Chinese Medicine (TCM).
Luigi Manni +4 more
openaire +4 more sources
The aim of this review is to report recent findings and ongoing studies on the effects of acupuncture on endogenous biological mediators, in particular on neurotrophins such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Acupuncture is a therapeutic technique and is a part of Traditional Chinese Medicine (TCM).
Luigi Manni +4 more
openaire +4 more sources
Neurotrophins and neurodegeneration
Neuropathology and Applied Neurobiology, 2003There is growing evidence that reduced neurotrophic support is a significant factor in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS). In this review we discuss the structure and functions of neurotrophins such as nerve growth factor, and the role of ...
Dawbarn, D, Allen, SJ
openaire +3 more sources