Results 71 to 80 of about 53,997 (300)

Retinoic acid triazole promotes neurotrophin-mediated cell growth and proliferation in nerve cells

Bangladesh Journal of Pharmacology, 2014
In the present study, fluorophenyl retinoic acid triazole, a retinoic acid derivative having more bioavailability compared to the parent retinoic acid was investigated against cell growth and proliferation.
Hui Shi, Yan Xiao Long, Yi Zhang, Ming Zhong, Kuang Zheng   +4 more
doaj  

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells

Frontiers in Immunology, 2017
Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła, Cornelia Richter, Martin Ryser, Arshad Jamal, Arshad Jamal, Michelle P. Ashton, Malte von Bonin, Malte von Bonin, Malte von Bonin, Matthias Kuhn, Benjamin Dorschner, Dimitra Alexopoulou, Katrin Navratiel, Ingo Roeder, Andreas Dahl, Christian M. Hedrich, Ezio Bonifacio, Sebastian Brenner, Sebastian Brenner, Sebastian Thieme   +19 more
doaj   +1 more source

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Association of carriers of single nucleotide polymorphisms rs1143634 and rs16944 in gene Il-1B and rs6265 in gene BDNF with temporal lobe epilepsy

Неврология, нейропсихиатрия, психосоматика, 2020
Temporal lobe epilepsy (TLE) is one of the most common and refractory forms of epilepsy, with a different etiology. According to experimental and clinical studies, the transformation of the normal pattern of brain neuron activity into paroxysmal is ...
Y. S. Panina, D. V. Dmitrenko, N. A. Shnayder, E. V. Egorova, A. A. Usoltseva   +4 more
doaj  

Contribution of Neurotrophins to the Immune System Regulation and Possible Connection to Alcohol Addiction

Biology, 2020
The first references to neurotrophic factors date back to the middle of the 20th century when the nerve growth factor (NGF) was first discovered. Later studies delivered a large amount of data on neurotrophic factors.
Evgenii M. Kozlov, Andrey V. Grechko, Yegor S. Chegodaev, Wei-Kai Wu, Alexander N. Orekhov   +4 more
doaj   +1 more source

p75 Neurotrophin Receptor Cleavage by α- and γ-Secretases Is Required for Neurotrophin-mediated Proliferation of Brain Tumor-initiating Cells*

Journal of Biological Chemistry, 2014
Background: p75 neurotrophin receptor (p75NTR) is an important mediator of invasion of malignant gliomas, but its role in glioma proliferation is unknown. Results: p75NTR mediates proliferation of brain tumor-initiating cells (BTICs) via its cleavage and
P. Forsyth, P. Forsyth, N. Krishna, Samuel O. Lawn, J. G. Valadez, Xiaotao Qu, D. Fenstermacher, M. Fournier, Lisa Potthast, P. Chinnaiyan, G. Gibney, M. Zeinieh, P. Barker, B. Carter, M. K. Cooper, R. Kenchappa, R. Kenchappa   +16 more
semanticscholar   +1 more source

Neurotrophins and the immune system [PDF]

Journal of Anatomy, 2003
AbstractThe neurotrophins are a family of polypeptide growth factors that are essential for the development and maintenance of the vertebrate nervous system. In recent years, data have emerged indicating that neurotrophins could have a broader role than their name might suggest.
VEGA JA, GARCIA, Olivia, HANNESTAD J, PEREZ PEREZ M, GERMANA', Antonino   +4 more
openaire   +4 more sources

Neurotrophin and Neurotrophin Receptor Involvement in Human Neuroblastoma [PDF]

, 2013
Neuroblastoma (NB) is an embryonic tumour that originates from cells of the neural crest (NC) arrested in their differentiation at different stages along the sympatho-adrenal lineage and, less frequently, from precursors of sensory neurons [1, 2]. As a consequence, NB can occur throughout the sympathetic chain from thoracic, abdominal and pelvic sites ...
RUGGERI, PIERDOMENICO, FARINA, ANTONIETTA, CAPPABIANCA, LUCIA ANNAMARIA, DI IANNI, NATALIA, RAGONE, MARZIA, MEROLLE, STEFANIA, Gulino, A, Mackay, A. R.   +7 more
openaire   +4 more sources

Elp1 function in placode‐derived neurons is critical for proper trigeminal ganglion development

Developmental Dynamics, EarlyView.
Abstract Background The trigeminal nerve is the largest cranial nerve and functions in somatosensation. Cell bodies of this nerve are positioned in the trigeminal ganglion, which arises from the coalescence of neural crest and placode cells. While this dual cellular origin has been known for decades, the molecular mechanisms controlling trigeminal ...
Margaret A. Hines, Lisa A. Taneyhill
wiley   +1 more source