Results 71 to 80 of about 55,877 (286)
Frontiers in Molecular Neuroscience, 2018 The p75 neurotrophin receptor (p75NTR), also known as low-affinity nerve growth factor, belongs to the tumor necrosis factor family of receptors. p75NTR is widely expressed in the nervous system during the development, as well as, in the neural crest ...
Sabine Wislet +3 more
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Frontiers in Molecular Neuroscience, 2020 Purpose: The aim of this study was to evaluate the potential neurotrophic factors and expression of neurotrophin receptors in peripheral blood mononuclear cells linked with the antidepressant action of exercise intervention during protracted ...
Jue Yang +11 more
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Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
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Frontiers in Physiology, 2017 Brain-derived neurotrophic factor (BDNF) is a major orchestrator of exercise-induced brain plasticity and circulating (peripheral) BDNF may have central effects.
Jeremy J. Walsh +3 more
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Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila central nervous system
Nature Neuroscience, 2013 Neurotrophin receptors corresponding to vertebrate Trk, p75NTR or Sortilin have not been identified in Drosophila, thus it is unknown how neurotrophism may be implemented in insects.
G. McIlroy +7 more
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Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial
Movement Disorders, EarlyView.Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess +15 more
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Retinoic acid triazole promotes neurotrophin-mediated cell growth and proliferation in nerve cells
Bangladesh Journal of Pharmacology, 2014 In the present study, fluorophenyl retinoic acid triazole, a retinoic acid derivative having more bioavailability compared to the parent retinoic acid was investigated against cell growth and proliferation.
Hui Shi +4 more
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The role of neurotrophic factors in retinal ganglion cell resiliency
Frontiers in Cellular NeuroscienceMany retinal diseases are characterized by direct or indirect retinal ganglion cell (RGC) neurodegeneration. In glaucoma and optic nerve neuropathies, RGCs are the primary affected cells, whereas in photoreceptor dystrophies, RGC loss is secondary to the
Alan K. Abraham +3 more
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Molecular Nutrition &Food Research, EarlyView.Paired peripheral‐blood RNA‐seq from MiBLEND was deconvolved with CIBERSORTx to profile leukocyte composition and cell‐type‐specific transcriptomic responses to seven fruit‐and‐vegetable blends. Deconvolution yielded 22 leukocyte subtypes that correlated with laboratory WBC reports (R = 0.886, p ≤ 0.01).
Yueqin He +3 more
wiley +1 more source
COX‐2/PGE2 axis regulates hippocampal BDNF/TrkB signaling via EP2 receptor after prolonged seizures
Epilepsia Open, 2020 Objective The objective of this study was to identify the signaling pathway that is immediately triggered by status epilepticus (SE) and in turn contributes to the excessive brain‐derived neurotrophic factor (BDNF)/tropomyosin‐related kinase receptor B ...
Ying Yu, Jianxiong Jiang
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