Results 81 to 90 of about 38,429 (260)
Brain-derived neurotrophic factor (BDNF) is a major orchestrator of exercise-induced brain plasticity and circulating (peripheral) BDNF may have central effects.
Jeremy J. Walsh+3 more
doaj +1 more source
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Editorial: Novel therapeutic targets for lower urinary tract symptoms
Jianshu Ni, Baojun Gu, Naoki Yoshimura
doaj +1 more source
Abstract Objective Fat taste sensitivity has been implicated in long‐term weight loss after bariatric surgery. Unexpectedly, improvement of orosensory fat acuity was not systematic in operated patients. Methods Obesity‐induced alterations of gene expression in gustatory papillae having been recently reported, we have explored the fungiform ...
Arnaud Bernard+5 more
wiley +1 more source
NT-4 Gene Expression of Male Wistar Rat’s Sciatic Nerve Fiber: The Effect of Decreased Activity on the Form of Spinal Nerve Ligation [PDF]
Background & Objectives: Painful neuropathy is a state resulting from somatosensory disease or injury. Neurotrophins such as NT-4 are crucial for neural growth and development and protect the integrity of function and structure of nervous system.
M Rahmati+4 more
doaj
Conductive Materials and Electrical Stimulation for Auditory Restoration
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao+8 more
wiley +1 more source
Neurotrophins and Psychiatric Disorders
Increasing number of studies has during the last decade linked neurotrophic factors with the pathophysiology of neuropsychiatric disorders and with the mechanisms of action of drugs used for the treatment of these disorders. In particular, brain-derived neurotrophic factor BDNF and its receptor TrkB have been connected with the pathophysiology in mood ...
Eero Castrén, Eero Castrén
openaire +4 more sources
A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly
ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan+5 more
wiley +1 more source
Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine [PDF]
Mathew T. Martin‐Iverson+2 more
openalex +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source