Results 81 to 90 of about 72,847 (330)

Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]

open access: yes, 2017
The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica   +9 more
core   +2 more sources

Silk fibroin‐based biomaterials for spinal cord injury repair: Recent advances and future prospects

open access: yesBMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of silk fibroin‐based biomaterials in spinal cord injury repair, focusing on environmentally friendly processing techniques, and the strategies for designing composite scaffolds as well as discussing the advantages and current challenges of silk fibroin‐based biomaterials in spinal ...
Xiaoliang Cui   +7 more
wiley   +1 more source

Irisin, Brain-Derived Neurotrophic Factor (BDNF), and Redox Balance in Geriatric Dynapenia

open access: yesAntioxidants
Irisin and brain-derived neurotrophic factor (BDNF) are considered potential biomarkers for sarcopenia; however, their interplay and relationship with oxidative stress remain unclear. Therefore, the aim of this study was to assess the serum concentration
Aleksandra Wojszel   +5 more
doaj   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf   +9 more
wiley   +1 more source

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells

open access: yesFrontiers in Immunology, 2017
Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła   +19 more
doaj   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore   +7 more
wiley   +1 more source

Short- and Long-Term Effects of Subchronic Stress Exposure in Male and Female Brain-Derived Neurotrophic Factor Knock-In Val66Met Mice

open access: yesBiology
Stress is an important risk factor for the onset of anxiety and depression. The ability to cope with stressful events varies among different subjects, probably depending on different genetic variants, sex and previous life experiences.
Fernando Antonio Costa Xavier   +3 more
doaj   +1 more source

Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]

open access: yes, 2001
Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P   +3 more
core   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

open access: yesIbrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou   +6 more
wiley   +1 more source

NGF in Neuropathic Pain: Understanding Its Role and Therapeutic Opportunities

open access: yesCurrent Issues in Molecular Biology
Nerve growth factor (NGF) is one of the essential components that have been implicated in the pathophysiology of neuropathic pain, a condition that develops following nerve injury or dysfunction.
Mario García-Domínguez
doaj   +1 more source

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