Results 121 to 130 of about 47,357 (330)

Neurotrophin and Neurotrophin Receptors in Human Fetal Kidney

open access: yesDevelopmental Biology, 1996
Vertebrate kidney development involves a series of complex interactions between the ureteric bud and undifferentiated mesenchyme resulting in the production of the nephron unit. These interactions are thought to be dependent on a variety of locally derived soluble factors, including peptide growth factors and their receptors.
Huber, L.Julie   +2 more
openaire   +2 more sources

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

open access: yes, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. [PDF]

open access: yes, 2015
Cancer stem cells (CSCs) are considered to be the cause of tumor initiation, metastasis and recurrence. Additionally, CSCs are responsible for the failure of chemotherapy and radiotherapy.
Chen, Xinfeng   +12 more
core  

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante   +4 more
wiley   +1 more source

Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin [PDF]

open access: gold, 2020
Nádia Pereira Gonçalves   +7 more
openalex   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

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