Results 21 to 30 of about 44,486 (289)
Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity
Abstract Nerve growth factor (NGF) is a neurotrophin that has been implicated in pain signaling, apoptosis, inflammation and proliferation. The resultant effects depend on interaction with two different receptors; tyrosine kinase A (TrkA) and p75NTR. NGF increases in synovial fluid from osteoarthritic joints, and monoclonal antibody therapy is trialed ...
Anna Kendall+2 more
wiley +1 more source
This manuscript reviews the function and fundamental characteristics of the neurotrophins and their receptors to introduce the reader to the differential effects exhibited by the neurotrophins; brain-derived neurotrophic factor and neurotrophin 4/5 when ...
Elizabeth Hernandez-Echeagaray
doaj +1 more source
Expression of Neurotrophins and Their Receptors Tropomyosin-related kinases (Trk) under Tension-stress during Distraction Osteogenesis [PDF]
The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation.
Aiga, Ayako+6 more
core +1 more source
Recent advances in understanding neurotrophin signaling [version 1; referees: 2 approved]
The nerve growth factor family of growth factors, collectively known as neurotrophins, are evolutionarily ancient regulators with an enormous range of biological functions.
Mark Bothwell
doaj +1 more source
Agathisflavone is a flavonoid with anti-neuroinflammatory and myelinogenic properties, being also capable to induce neurogenesis. This study evaluated the therapeutic effects of agathisflavone—both as a pharmacological therapy administered in vivo and as
Ravena P. do Nascimento+16 more
doaj +1 more source
Drosophila Neurotrophins Reveal a Common Mechanism for Nervous System Formation [PDF]
Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival ...
Aberle+136 more
core +3 more sources
Abstract Background Inflammation may increase stress, while stress may promote inflammation. Most dermatological conditions are chronic and inflammatory, while some, such as cancer, naevi and tumours are non‐inflammatory, but may cause stress because of the fear of malignancy and the necessity for surgical and other invasive treatments.
Flora Balieva+7 more
wiley +1 more source
Angiogenesis in Gynecological Cancers: Role of Neurotrophins
Angiogenesis, or generation of new blood vessels from other pre-existing, is a key process to maintain the supply of nutrients and oxygen in tissues. Unfortunately, this process is exacerbated in pathologies such as retinopathies and cancers with high ...
Maritza P. Garrido+6 more
doaj +1 more source
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María+4 more
core +4 more sources
The self-organization of combinatoriality and phonotactics in vocalization systems [PDF]
This paper shows how a society of agents can self-organize a shared vocalization system that is discrete, combinatorial and has a form of primitive phonotactics, starting from holistic inarticulate vocalizations. The originality of the system is that: (1)
Oudeyer, Dr. P-Y.
core +1 more source