Results 41 to 50 of about 47,357 (330)

mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening

open access: yesBiomedicines, 2022
The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea pigs,
Annamaria Tisi   +4 more
doaj   +1 more source

Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings [PDF]

open access: yesBrazilian Journal of Psychiatry, 2020
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment.
Giselli Scaini   +6 more
doaj   +1 more source

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

open access: yes, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela   +5 more
core   +1 more source

Biomimetic Approaches for Separated Regeneration of Sensory and Motor Fibers in Amputee People: Necessary Conditions for Functional Integration of Sensory–Motor Prostheses With the Peripheral Nerves

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The regenerative capacity of the peripheral nervous system after an injury is limited, and a complete function is not recovered, mainly due to the loss of nerve tissue after the injury that causes a separation between the nerve ends and to the ...
Atocha Guedan-Duran   +20 more
doaj   +1 more source

Functional Diversity of Neurotrophin Actions on the Oculomotor System [PDF]

open access: yes, 2016
Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance of appropriate adult neuronal circuits and phenotypes.
Benítez Temiño, Beatriz   +5 more
core   +1 more source

The Effects of Nordic Walking With Poles With an Integrated Resistance Shock Absorber on Cognitive Abilities and Cardiopulmonary Efficiency in Postmenopausal Women

open access: yesFrontiers in Aging Neuroscience, 2020
Late adulthood is associated with atrophy of brain areas, which contribute to cognitive deterioration and increase the risk of depression. On the other hand, aerobic exercise can improve learning and memory function, ameliorate mood, and prevent ...
Katarzyna Domaszewska   +6 more
doaj   +1 more source

Long-Term Consequences of Developmental Alcohol Exposure on Brain Structure and Function: Therapeutic Benefits of Physical Activity

open access: yesBrain Sciences, 2012
Developmental alcohol exposure both early in life and during adolescence can have a devastating impact on normal brain structure and functioning, leading to behavioral and cognitive impairments that persist throughout the lifespan.
Gillian F. Hamilton   +2 more
doaj   +1 more source

Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis

open access: yesInternational Archives of Otorhinolaryngology, 2023
Introduction The nonspecific hyperreactivity of rhinitis has been attributed to neurotrophins activating sensory nerves and inflammatory cells.
Thiago Carvalho   +6 more
doaj   +1 more source

The effect of vascular graft and human umbilical cord blood-derived CD34+ stem cell on peripheral nerve healing [PDF]

open access: yes, 2018
AIM: There are many trials concerning peripheral nerve damage causes and treatment options. Unfortunately, nerve damage is still a major problem regarding health, social and economic issues.
Abban, G.   +6 more
core   +1 more source

PLG Bridge Implantation in Chronic SCI Promotes Axonal Elongation and Myelination. [PDF]

open access: yes, 2019
Spinal cord injury (SCI) is a devastating condition that may cause permanent functional loss below the level of injury, including paralysis and loss of bladder, bowel, and sexual function.
Anderson, Aileen J   +8 more
core   +1 more source

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