Results 171 to 180 of about 12,090 (225)

Hemichordate neurulation and the origin of the neural tube [PDF]

Nature Communications, 2013
The origin of the body plan of our own phylum, Chordata, is one of the most fascinating questions in evolutionary biology. Yet, after more than a century of debate, the evolutionary origins of the neural tube and notochord remain unclear. Here we examine
Norio Miyamoto
exaly   +2 more sources

Embryo model completes gastrulation to neurulation and organogenesis

Nature, 2022
AbstractEmbryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembryonic endoderm stem (XEN) cells and inducible XEN (iXEN) cells6–11.
Gianluca Amadei, Charlotte Handford, Chengxiang Qiu   +2 more
exaly   +5 more sources

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Neurulation in the rabbit embryo

Anatomy and Embryology, 1998
Among a broad range of factors and mechanisms involved in the complex process of neurulation a relationship between the curvature of the craniocaudal body axis and rate of neural tube closure has been proposed, but more examples and models are needed to further substantiate the existence of this relationship.
M C, Peeters, C, Viebahn, J W, Hekking, H W, van Straaten   +3 more
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Calcium and neurulation in mammalian embryos

Development, 1985
ABSTRACT The role of calcium in neurulation in rat embryos has been studied. Rat embryos at 10-4 days of gestation, when the cephalic neural folds have elevated but not fused, have been cultured in various media, and the effects of these media on the morphology of the cephalic neural folds have been observed by scanning and transmission ...
M J, Smedley, M, Stanisstreet
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A simple molecular model of neurulation

BioEssays, 1998
A molecular model for the morphogenesis of the central nervous system is built and solved by computer. The formalism rests on molecular-biological data gathered from insects and vertebrates during neural differentiation and neuronal fate specification.
M, Kerszberg, J P, Changeux
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Secondary Neurulation Defects: Retained Medullary Cord

2023
Retained medullary cord (RMC) is a defect resulting from impaired secondary neurulation. Intraoperatively, RMC is recognizable as an elongated cord-like structure caudal to the conus, that contains histologically confirmed neuroglial components and a lumen with an ependymal lining. It characteristically does not possess neurological function.
Kyung Hyun, Kim, Ji Yeoun, Lee, Kyu-Chang, Wang   +2 more
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Strychnine induces embryotoxicity in rat neurulation

Neurotoxicology and Teratology, 2005
Administering strychnine, a potent antagonist of glycine receptors, to pregnant rats caused marked toxic effects on the ensuing embryos. The embryotoxic effects of strychnine were compared with those induced by retinal palmitate during rat neurulation; and it was found that strychnine was stronger than retinal palmitate in a number of abnormalities ...
Guadalupe, García-Alcocer, Ataúlfo, Martínez-Torres, Ricardo, Miledi   +2 more
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Stem cell-derived models of spinal neurulation

Emerging Topics in Life Sciences, 2023
Neurulation is a critical step in early embryonic development, giving rise to the neural tube, the primordium of the central nervous system in amniotes. Understanding this complex, multi-scale, multi-tissue morphogenetic process is essential to provide insights into normal development and the etiology of neural tube defects.
Camil Mirdass, Martin Catala, Mikaëlle Bocel, Stéphane Nedelec, Vanessa Ribes   +4 more
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Midkine and secondary neurulation

Teratology, 1997
Midkine (MK) is a growth factor with documented neurotrophic activity for central nervous system neurons. It has also been shown to induce conversion of pluripotent mesenchymal P19 embryonic carcinoma cells into neuroepithelial derivatives. During the development of the chick embryonic neuraxis, two separate events occur.
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Neurulation and Neural Tube Closure Defects

2003
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Copp, Andrew J., Cogram, Patricia, Fleming, A., Gerrelli, D., Henderson, Deborah J., Hynes, A., Kolatsi-Joannou, M., Murdoch, J, Ybot, Patricia   +8 more
openaire   +3 more sources