Results 81 to 90 of about 454,570 (346)

Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Hyperimmune Immunoglobulin Demonstrates Potent Neutralization and Antibody-Dependent Cellular Cytotoxicity and Phagocytosis Through N and S Proteins [PDF]

open access: bronze, 2021
José María Soberanes Díez   +10 more
openalex   +1 more source

A simple protein-based surrogate neutralization assay for SARS-CoV-2

open access: yesbioRxiv, 2020
Most of the patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mount a humoral immune response to the virus within a few weeks of infection, but the duration of this response and how it correlates with clinical outcomes ...
K. Abe   +22 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Cross-Reactive Mouse Monoclonal Antibody against Rhinovirus Mediates Phagocytosis In Vitro

open access: yesProceedings, 2020
Human rhinoviruses (RVs) are the main cause of the common cold worldwide. To date, more than 160 serotypes of the virus have been recognized. These viruses are categorized into three major groups: A, B, and C.
Mohammad Amin Behzadi   +6 more
doaj   +1 more source

State Neutrality [PDF]

open access: yes, 2012
This article attempts to spell out the main tenets of the principle of state neutrality and to explain how they hang together. It examines the central objections, and explores revisions that may enhance the theory's defensibility. Specifically, it discusses neutrality as non-discrimination, neutrality as shared reasons, objections to liberal neutrality,
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Neutralization with Simultaneous Separation of Metallic Ions from Condensed Water Through Capillary Polypropylene and Cellulose Derivatives

open access: yesProceedings, 2020
An interesting and unpredictable environmental issue raises condensing plants. [...]
Anca -Maria Cimbru   +3 more
doaj   +1 more source

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

open access: yesNature, 2021
D. Planas   +28 more
semanticscholar   +1 more source

Structural basis for broad coronavirus neutralization

open access: yesNature Structural & Molecular Biology, 2020
Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past two decades: SARS-CoV, MERS-CoV and SARS-CoV-2. To evaluate the possibility of identifying antibodies with broad neutralizing activity, we isolated a ...
M. M. Sauer   +14 more
semanticscholar   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich   +10 more
wiley   +1 more source

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