Results 161 to 170 of about 312,346 (337)

704/DNA vaccines leverage cytoplasmic DNA stimulation to promote anti-HIV neutralizing antibody production in mice and strong immune response against alpha-fetoprotein in non-human primates [PDF]

, 2023
Thibault Colombani, Thomas Haudebourg, Bruno Pitard   +2 more
openalex   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

VH3-53/66-Class RBD-Specific Human Monoclonal Antibody iB20 Displays Cross-Neutralizing Activity against Emerging SARS-CoV-2 Lineages [PDF]

, 2022
Sergey V. Kulemzin, Maria V. Sergeeva, Konstantin O. Baranov, Andrey A. Gorchakov, Sergey V. Guselnikov, Tatyana N. Belovezhets, Olga Y. Volkova, Alexander M. Najakshin, Nikolai A. Chikaev, Daria Danilenko, Alexander V. Taranin   +10 more
openalex   +1 more source

Neutralization of HIV-1 by antibody

Current Opinion in Immunology, 1996
The humoral immune response to HIV-1 has been extensively studied over the past few years and considerable advances have been made in understanding the dynamics and specificity of the neutralizing antibody component during and after seroconversion. Despite this, there is still no clear understanding of the role of neutralizing antibodies in controlling
openaire   +2 more sources

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

The PreS-Based Recombinant Vaccine VVX001 Induces Hepatitis B Virus Neutralizing Antibodies in a Low-Responder to HBsAg-Based HBV Vaccines [PDF]

Inna Tulaeva, Felix Lehmann, Nora Goldmann, Alexandra Dubovets, Daria Trifonova, Mikhail Tulaev, Carolin Cornelius, Milena Weber, Margarete Focke‐Tejkl, А. В. Караулов, Rainer Henning, David Niklas Springer, Ursula Wiedermann, Dieter Glebe, Rudolf Valenta   +14 more
openalex   +1 more source

Clearance of a persistent paramyxovirus infection is mediated by cellular immune responses but not by serum-neutralizing antibody [PDF]

, 1990
D. F. Young, Richard E. Randall, J. Hoyle, B.E. Souberbielle   +3 more
openalex   +1 more source

Detection of Neutralizing Antibodies against SARS-CoV-2 Post-Vaccination in Health Care Workers of a Large Tertiary Hospital in Spain by Using a Rapid Test LFIC and sVNT-ELISA [PDF]

, 2022
José Tuells, Mónica Parra-Grande, Francisco J. Santos-Calle, Ana C. Montagud, Cecilia Egoavil, Celia García-Rivera, Pablo Caballero, Eva María Gabaldón Bravo, Juan Carlos Rodrı́guez, José Antonio Hurtado Sánchez   +9 more
openalex   +1 more source

Neutralizing antibodies in convalescent patients [PDF]

Nature Reviews Immunology, 2020
Uhl, LFK, Chauveau, A
openaire   +3 more sources