Results 181 to 190 of about 1,883,437 (383)

Function and structure of broadly neutralizing antibodies against SARS-CoV-2 Omicron variants isolated from prototype strain infected convalescents

Journal of Translational Medicine
Background The ongoing emergence of evolving SARS-CoV-2 variants poses great threaten to the efficacy of authorized monoclonal antibody-based passive immunization or treatments. Developing potent broadly neutralizing antibodies (bNabs) against SARS-CoV-2
Dan Li, Caiqin Hu, Junwei Su, Shuo Du, Ying Zhang, Wanqi Ni, Li Ren, Yanling Hao, Yi Feng, Changzhong Jin, Shuo Wang, Xinxian Dai, Zheng Wang, Biao Zhu, Junyu Xiao, Yiming Shao   +15 more
doaj   +1 more source

Performance evaluation of four kits for the detection of neutralizing antibody against SARS-CoV-2 in human serum

Journal of Clinical Virology Plus
To evaluate four novel SARS-CoV-2 neutralizing antibody assay kits' application in neutralizing antibodies of population. Questionnaires from the voluntary participating researchers and selected the qualified questionnaires to analyse.
Hui Zhen, Ya Cheng, Qimeng Sun, Ying Zheng, Lili Tian, Chao Shen, Li Li, Jie Gong, Yonggang Chen, Hongping Ba   +9 more
doaj   +1 more source

Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom [PDF]

, 2017
Jinhua Liu, Qiyi He, Wenwen Wang, Bin Zhou, Bo Li, Yingfeng Zhang, Cong Luo, Diancheng Chen, Jia Tang, YU Xiao-dong   +9 more
openalex   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Nsp2 and GP5-M of Porcine Reproductive and Respiratory Syndrome Virus Contribute to Targets for Neutralizing Antibodies [PDF]

, 2019
Jia Su, Lei Zhou, Bicheng He, Xinhui Zhang, Xinna Ge, Jun Han, Xin Guo, Hanchun Yang   +7 more
openalex   +1 more source

COVID‐19: are neutralizing antibodies neutralizing enough? [PDF]

Transfusion, 2020
openaire   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Protective effect of a germline, IL‐17‐neutralizing antibody in murine models of autoimmune inflammatory disease [PDF]

, 2014
Kiran Dallenbach, Patrik Maurer, Till A. Röhn, Franziska Zabel, Manfred Köpf, Martin F. Bachmann   +5 more
openalex   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Age-specific kinetics of neutralizing antibodies and infection enhancement among ≤1 year-old Indian infants

Frontiers in Cellular and Infection Microbiology
BackgroundInfants born to dengue-immune mothers acquire maternal antibodies to dengue. Maternal antibodies decline over time, making infants susceptible to primary dengue infections. Another important concern is the role of maternal antibodies in causing
Shweta Chelluboina, Akhilesh Chandra Mishra, Vidya Avinash Arankalle, Shubham Shrivastava   +3 more
doaj   +1 more source