Results 11 to 20 of about 688,534 (290)

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

Clostridioides difficile aggravates dextran sulfate solution (DSS)-induced colitis by shaping the gut microbiota and promoting neutrophil recruitment

Gut Microbes, 2023
Clostridioides difficile is a pathogen contributing to increased morbidity and mortality of patients with inflammatory bowel disease (IBD). To determine how C.
Danfeng Dong, Tongxuan Su, Wei Chen, Daosheng Wang, YiLun Xue, Qiuya Lu, Cen Jiang, Qi Ni, Enqiang Mao, Yibing Peng   +9 more
doaj   +1 more source

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis

Acta Dermato-Venereologica, 2023
Crisaborole, a phosphodiesterase 4 (PDE4) inhibitor, has been approved for the treatment of mild to moderate atopic dermatitis. Atopic dermatitis is often associated with increased pain.
Darya Pavlenko, Zeynep Todurga Seven, Lauren Bystrom, Anika Markan, Rebecca Verpile, Hirotake Ishida, Tasuku Akiyama   +6 more
doaj   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2013
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross, A G Rossi, A Planaguma, AE Leitch, AE Leitch, AG Rossi, AL Alessandri, B Dibbert, BM Fournier, C Akgul, C D Lucas, C Haslett, C Nathan, C T Robb, CD Lucas, CN Serhan, D A Dorward, DA Dorward, DA Moulding, DA Moulding, DA Steimer, DJ Wardle, E Abraham, EE McGrath, GL Bannenberg, GS Worthen, H Liu, HG Folkesson, HM Marriott, I Dzhagalov St, I Nicoletti, J A Marwick, J Liang, JS Savill, K C Allen, K Ganeshan, KP Steinberg, L Fialkow, L Santo, M A Tait, MA Matthay, N Chiang, N Fotouhi-Ardakani, N Hirani, O Eickmeier, R Boxio, R Duffin, S Brode, S Fox, S Fox, S Michlewska, SJ Leuenroth, SL Poe, SP Garrison, T Hideshima, T Tanaka, TR Ulich, U Koedel, Y Liu   +58 more
core   +1 more source

Neutrophil-to-lymphocyte ratio: A surrogate marker for prognosis of oral squamous cell carcinoma

Indian Journal of Medical and Paediatric Oncology, 2018
Context: Recent studies show that enzymatic contents of the neutrophil granules have a remarkable ability to modulate the tumor microenvironment by causing apoptosis of T-lymphocytes which leaves the host's cell-mediated immunity at stake.
R Mahalakshmi, Karen Boaz, N Srikant, Mohan Baliga, Premalatha Shetty, Mukul Prasad, Shweta Yellapurkar, Amitha J Lewis   +7 more
doaj   +1 more source

Changes in eotaxin-2 and periostin levels in patients with bronchial asthma according to their smoking status: a cross-sectional study

Egyptian Journal of Chest Disease and Tuberculosis, 2023
Background Smoking influences the nature of airway inflammation in patients with bronchial asthma though synthesis of certain cytokines. Patterns of bronchial asthma are differentiated clinically, functionally, and regarding inflammatory biomarkers.
Mohammed F Abdelghany, Atef F El-Karn, Mahmoud F Sherif, Mohamed I Seddik, Safaa A Eid, Sahar F Youssif   +5 more
doaj   +1 more source

The association of neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio with 3-month clinical outcome after mechanical thrombectomy following stroke [PDF]

, 2020
Background and aim Neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) are associated with clinical outcomes in malignancy, cardiovascular disease and stroke.
Alakbarzade, V, Bridge, L, Clark, CN, Clarke, B, Khan, U, Lux, D, Pereira, AC, Zhang, L   +7 more
core   +1 more source

Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Lung injury, a severe adverse outcome of lipopolysaccharide‐induced acute respiratory distress syndrome, is attributed to excessive neutrophil recruitment and effector response.
Ziwei Ou, Elena Dolmatova, Rohan Mandavilli, Hongyan Qu, Georgette Gafford, Taylor White, Alejandra Valdivia, Bernard Lassègue, Marina S. Hernandes, Kathy K. Griendling   +9 more
doaj   +1 more source

Neutrophilic thrombophagocytosis

Morphologie, 2020
Platelets phagocytosed by neutrophils is a rare morphological finding on peripheral blood films. It is rarely an EDTA-dependent artifact but mainly caused by an active vascular inflammation process. Here is reported an unexpected observation of neutrophilic thrombophagocytosis, in the context of a disseminated Streptococcus pneumoniae infection.
I, Amouroux, J F, Lesesve
openaire   +3 more sources