Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Lung injury, a severe adverse outcome of lipopolysaccharide‐induced acute respiratory distress syndrome, is attributed to excessive neutrophil recruitment and effector response.
Ziwei Ou +9 more
doaj +1 more source
Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia [PDF]
, 2002 Heterozygous mutations in neutrophil elastase have been detected in many sporadic cases of congenital neutropenia. However, a convincing pathogenetic mechanism has not been established, and it is unclear whether the effects of the mutant enzyme occur ...
Ancliff, PJ +13 more
core +1 more source
Pocket ACEs: Discovering new function within an old player
Frontiers in Physiology, 2023 Angiotensin-converting enzyme (ACE) is canonically known for its role in the renin-angiotensin system (RAS) where its conversion of angiotensin I (Ang I) to the bioactive peptide angiotensin II (Ang II) helps to regulate blood pressure, electrolyte, and ...
Matthew Leong, Xiaomo Li, Manita Chaum
doaj +1 more source
Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]
, 2009 During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg +20 more
core +1 more source
Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]
, 2009 Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Alexander Georg Khandoga +15 more
core +1 more source
Neutrophil-lymphocyte ratio change after curative gastrectomy for gastric cancer: a subgroup analysis [PDF]
, 2020 Objective: To evaluate the impact of neutrophil-lymphocyte ratio change after curative surgery for gastric cancer. Methods: A retrospective analysis of patients with gastric cancer who underwent curative surgery between 2009 and 2017 was performed.
André Roncon Dias (8046026) +6 more
core +1 more source
Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice [PDF]
, 2017 Objective. Proline-serine-threonine-phosphatase-interacting protein 2 (PSTPIP2) is involved in macrophage activation, neutrophil motility and osteoclast differentiation.
Liao, Hsiu-Jung;Chyuan, I-Tsu;Wu, Chien-Sheng;Lin, Shu-Wha;Chen, Kun-Hung;Tsai, Hwei-Fang;Hsu, Ping-Ning +1 more
core +1 more source
Can Neutrophil Count, Lymhocyte Count and Neutrophil-tolymphocyte Ratio Predict Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors? [PDF]
, 2020 Objective: To examine the relationship of neutrophil counts, lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) with postoperative fever in patients undergoing percutaneous nephrolithotomy (PCNL)
DEMİRTAŞ, TÜREV +9 more
core +1 more source
Immune complex-induced anti-inflammatory neutrophil functions [PDF]
, 2022 Neutrophils are short lived innate immune cells that perform a range of functions, including chemotaxis, phagocytosis, degranulation, generation of reactive oxygen species (ROS) and production of cytokines which equip them well to defending the host from
Karmakar, Utsa
core +1 more source
Neutrophilic thrombophagocytosis
Morphologie, 2020 Platelets phagocytosed by neutrophils is a rare morphological finding on peripheral blood films. It is rarely an EDTA-dependent artifact but mainly caused by an active vascular inflammation process. Here is reported an unexpected observation of neutrophilic thrombophagocytosis, in the context of a disseminated Streptococcus pneumoniae infection.
I, Amouroux, J F, Lesesve
openaire +3 more sources