Results 21 to 30 of about 416,964 (269)
Acta Dermato-Venereologica, 2023 Crisaborole, a phosphodiesterase 4 (PDE4) inhibitor, has been approved for the treatment of mild to moderate atopic dermatitis. Atopic dermatitis is often associated with increased pain.
Darya Pavlenko +6 more
doaj +1 more source
Neutrophil-to-lymphocyte ratio: A surrogate marker for prognosis of oral squamous cell carcinoma
Indian Journal of Medical and Paediatric Oncology, 2018 Context: Recent studies show that enzymatic contents of the neutrophil granules have a remarkable ability to modulate the tumor microenvironment by causing apoptosis of T-lymphocytes which leaves the host's cell-mediated immunity at stake.
R Mahalakshmi +7 more
doaj +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2023 Background Smoking influences the nature of airway inflammation in patients with bronchial asthma though synthesis of certain cytokines. Patterns of bronchial asthma are differentiated clinically, functionally, and regarding inflammatory biomarkers.
Mohammed F Abdelghany +5 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Lung injury, a severe adverse outcome of lipopolysaccharide‐induced acute respiratory distress syndrome, is attributed to excessive neutrophil recruitment and effector response.
Ziwei Ou +9 more
doaj +1 more source
Pocket ACEs: Discovering new function within an old player
Frontiers in Physiology, 2023 Angiotensin-converting enzyme (ACE) is canonically known for its role in the renin-angiotensin system (RAS) where its conversion of angiotensin I (Ang I) to the bioactive peptide angiotensin II (Ang II) helps to regulate blood pressure, electrolyte, and ...
Matthew Leong, Xiaomo Li, Manita Chaum
doaj +1 more source
Circulation Research, 2015 More than a century ago, in 1881, Bizzozero1 discovered platelets and their role in primary hemostasis. Since this founding study, it has been shown that, in addition to the scaffold of platelets and fibrin, other proteins and cells play an important role in thrombus formation and stabilization.
Jean-Baptiste, Michel +1 more
openaire +2 more sources
Cell Cycle, 2015 Neutrophils are short-lived effector cells of the innate immune system that form the first line of defense against microbial pathogens.1 Recent studies show that, by migrating to bone marrow, these cells can also induce (VACV)-specific T cell responses.2 Neutrophils polarize to distinct phenotypes in response to environmental cytokine/chemokine signals.
Mauro, Di Pilato, Mariano, Esteban
openaire +2 more sources
Effect of Lonomia obliqua Venom on Human Neutrophils
Toxins, 2021 The significant incidence of deforestation in South America culminates in the contact of humans with typical forests species. Among these species, one may highlight Lonomia obliqua caterpillar, which, when touched by humans, can poison them through their
João Alfredo Moraes +8 more
doaj +1 more source
Dysregulated Neutrophil Phenotype and Function in Hospitalised Non-ICU COVID-19 Pneumonia
Cells, 2022 Rationale: Infection with the SARS-CoV2 virus is associated with elevated neutrophil counts. Evidence of neutrophil dysfunction in COVID-19 is based on transcriptomics or single functional assays. Cell functions are interwoven pathways, and understanding
Kylie B. R. Belchamber +13 more
doaj +1 more source
ResearchThe diversity of neutrophils’ subtypes and functions in the tumor microenvironmentunderlies their contributions to both pro- and anti-tumorigenic activities.
Yunxi Yang +7 more
doaj +1 more source