Results 31 to 40 of about 688,534 (290)

Highly Selective Exogenous Neutrophils Effectively Inhibit Growth of Colon Cancer under the Guidance of Precision Navigation

Research
The diversity of neutrophils’ subtypes and functions in the tumor microenvironmentunderlies their contributions to both pro- and anti-tumorigenic activities.
Yunxi Yang, Chuyu Li, Yiming Shao, Xiao Wen, Cheng Lu, Xi Gao, Yiwen Mei, Bingwei Sun   +7 more
doaj   +1 more source

Three-dimensional migration of neutrophils through an electrospun nanofibrous membrane

BioTechniques, 2015
The study of immune cell migration is important for understanding the immune system network, which is associated with the response to foreign cells. Neutrophils act against foreign cells before any other immune cell, and they must be able to change shape
Songwan Jin, Tae-Min Park, Cho-Hee Kim, Jin-Soo Kim, Binh Duong Le, Young Hun Jeong, Jong-Young Kwak, Sik Yoon   +7 more
doaj   +1 more source

Neutrophil Activated by the Famous and Potent PMA (Phorbol Myristate Acetate)

Cells, 2022
This review will briefly outline the major signaling pathways in PMA-activated neutrophils. PMA is widely used to understand neutrophil pathways and formation of NETs.
Hylane Luiz Damascena, Wendy Ann Assis Silveira, Mariana S. Castro, Wagner Fontes   +3 more
doaj   +1 more source

Loss of testosterone impairs anti-tumor neutrophil function. [PDF]

, 2020
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent ...
Arditi, Moshe, Crother, Timothy R, Lane, Malcolm E, Luu, Michael, Markman, Janet L, Martinon, Daisy, Noval Rivas, Magali, Porritt, Rebecca A, Posadas, Edwin M, Wakita, Daiko   +9 more
core   +1 more source

Neutrophil microRNAs

Biological Reviews, 2023
ABSTRACTNeutrophils are considered ‘first‐line defence’ cells as they can be rapidly recruited to the site of the immune response. As key components of non‐specific immune mechanisms, neutrophils use phagocytosis, degranulation, and formation of neutrophil extracellular traps (NETs) to fight pathogens.
Marzena Garley, Karolina Nowak, Ewa Jabłońska   +2 more
openaire   +3 more sources

Dynamic CD177/CD10 ratio for infection diagnosis and mortality risk stratification in critically ill patients: a prospective cohort studyResearch in context

EBioMedicine
Summary: Background: Two crucial needs persist in delivering effective critical care: reliable differentiation of infectious vs non-infectious systemic inflammation and detection of impending sepsis before the occurrence of organ dysfunction.
Jiamin Huang, Keliang Xie, Heyue Li, Xiao Wen, Yiwen Mei, Jiahui Chen, Aixiang Yang, Bingwei Sun   +7 more
doaj   +1 more source

A New Product of Bilirubin Degradation by H₂O₂ and Its Formation in Activated Neutrophils and in an Inflammatory Mouse Model

Biomolecules, 2022
Bilirubin (BR) is a tetrapyrrolic compound stemming from heme catabolism with diverse physiological functions. It can be oxidized by H2O2 to form several degradation products, some of which have been detected in vivo and may contribute to the ...
Fei-Fei Yu, Yao Yuan, Yan Ao, Li Hua, Wu Wang, Yiyi Cao, Jing Xi, Yang Luan, Shangwei Hou, Xin-Yu Zhang   +9 more
doaj   +1 more source

Stimulation of endothelial adenosine Al receptors enhances adhesion of neutrophils in the intact guinea pig coronary system [PDF]

, 1994
Objective: The primary aim was to determine the action of pathophysiologically relevant adenosine concentrations (0.1-1 μM) on adhesion of neutrophils to coronary endothelium.
Becker, Bernhard F., Gerlach, E., Raschke, P., Zahler, Stefan   +3 more
core   +1 more source

Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]

, 2009
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson, Brown, Compton, Cooper, Crozier, Dukes, Forrest, Gabay, Gasser, Halazun, Hauser, Ishizuka, Kacevska, Kandemir, Kim, Kobayashi, Lee, Leitch, Lindmark, Maltoni, McMillan, McMillan, Mehrkhani, Michael, Moertel, Monreal, Morris, Petrelli, Ramsey, Roxburgh, Sasaki, Sharma, Smith, Taylor, Thynne, Vakkila, Vibert, Viganó, Walsh, Wanebo, Wang, Wolpin   +41 more
core   +1 more source

Neutrophil chemotaxis score and chemotaxis-related genes have the potential for clinical application to prognosticate the survival of patients with tumours

BMC Cancer
As frontline cells, the precise recruitment of neutrophils is crucial for resolving inflammation and maintaining the homeostasis of the organism. Increasing evidence suggests the pivotal role of neutrophil chemotaxis in cancer progression and metastasis.
Yunxi Yang, Jun Yang, Linbin Li, Yiming Shao, Lu Liu, Bingwei Sun   +5 more
doaj   +1 more source