Results 41 to 50 of about 548,170 (252)
Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]
, 2007 Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Small, Gary R. +9 more
core +1 more source
Immune complex-induced anti-inflammatory neutrophil functions [PDF]
, 2022 Neutrophils are short lived innate immune cells that perform a range of functions, including chemotaxis, phagocytosis, degranulation, generation of reactive oxygen species (ROS) and production of cytokines which equip them well to defending the host from
Karmakar, Utsa
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
PharmaceuticsObjective: F. nucleatum, a tumor-resident bacterium colonizing breast cancer (BC), results in an immunosuppressive microenvironment and facilitates tumor growth and metastasis.
Xinxin Chen +3 more
doaj +1 more source
Targeting Neutrophils in Sepsis: From Mechanism to Translation
Frontiers in Pharmacology, 2021 Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Although our understanding in the pathophysiological features of sepsis has increased significantly during the past decades, there is still lack of specific ...
Xiaofei Shen +5 more
doaj +1 more source
The effects of honey compared with sucrose and a sugar-free diet on neutrophil phagocytosis and lymphocyte numbers after long-term feeding in rats [PDF]
, 2007 To determine whether honey and sucrose would have differential effects on levels of neutrophil phagocytosis after long-term feeding 36 2-month old Sprague Dawley rats were fed a powdered diet that was either sugar-free or contained 7.9% sucrose or 10 ...
Lynne M Chepulis, Chepulis, Lynne Merran
core +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Scientific ReportsHashimoto’s Thyroiditis (HT) is an autoimmune disorder characterized by metabolic disturbances. However, a comprehensive metabolic and lipid profile of HT has not been reported.
Guoqiang Wang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Sari PediatriLatar belakang. Leukemia merupakan suatu penyakit keganasan sel darah yang berasal dari sumsum tulang. Toksisitas hematologi yang terjadi selama kemoterapi dapat memicu timbulnya perubahan neutrofil yang memunculkan manifestasi klinis sehingga menurunkan
Deta Putrimingtyas +2 more
doaj +1 more source