Results 151 to 160 of about 57,341 (275)

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, Volume 13, Issue 9, 13 February 2026.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Neutrophil Elastase (ELANE) as a Novel Neuroinflammatory Biomarker in Alcohol Use Disorder: Clinical Validation. [PDF]

Addict Biol
Zhang B, Zhang J, Zhu M, Fan Y, Xue Y.
europepmc   +1 more source

Rethinking Chronic Wound Treatment: Unlocking the Potential of Combination Products for an Unmet Multifactorial Need: A Review Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Chronic wounds, including diabetic foot, venous, and pressure ulcers, remain a major unmet medical challenge due to their prevalence, severity, and the limited efficacy of current treatments. These wounds are inherently multifactorial, requiring simultaneous intervention across all chronicity‐inducing factors.
Alberto Nicolás Ramos, Nicolás Cerusico, Romina Chavez‐Jara   +2 more
wiley   +1 more source

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley   +1 more source

A Novel Role of Neutrophil Elastase in Podocyte Dysfunction Induced by High Glucose, PMA, and MDP. [PDF]

J Cell Physiol
Kulesza T, Wróblewska A, Sawicka J, Audzeyenka I, Rachubik P, Rogacka D, Mallek W, Wysocka M, Lesner A, Piwkowska A.   +9 more
europepmc   +1 more source

Predictors of Intravenous Immunoglobulin Non‐Responsiveness in Children With Kawasaki Disease

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Compared to IVIG responders, the non‐responders showed significantly higher NLR, PLR, and SII (p‐values < 0.05). SII was a better IVIG‐NR predictor than NLR and PLR. ABSTRACT Background This retrospective study assesses whether the systemic immune‐inflammation index (SII) is a better predictor of intravenous immunoglobulin (IVIG) non‐responsiveness ...
Yun Cheng, Biquan Chen
wiley   +1 more source

Neutrophil Elastase Limits Spread of Staphylococcus aureus during Skin Infection. [PDF]

J Infect Dis
Kanoza M, Folkert J, Ciastoń I, Aliramezani A, Potempa J, Koziel J, Kwiecinski JM.   +6 more
europepmc   +1 more source

Impaired Phagocytosis in Peritonitis Exudate Secondary to Complement Consumption [PDF]

, 1988
Billing, A., Fröhlich, D., Jochum, Marianne, Kortmann, H.   +3 more
core   +1 more source

Neutrophil Elastase Modulates Cytokine Expression [PDF]

Journal of Biological Chemistry, 2012
Rym Benabid, Julien Wartelle, Laurette Malleret, Nicolas Guyot, Sophie Gangloff, François Lebargy, Azzaq Belaaouaj   +6 more
openaire   +1 more source

Systemic Effects of Vascular Photobiomodulation on Early Macrophage Recruitment During Skeletal Muscle Repair

Journal of Biophotonics, Volume 19, Issue 2, February 2026.
Preventive vascular photobiomodulation accelerates macrophage recruitment and enhances pro‐regenerative inflammation after skeletal muscle injury, suggesting its potential to improve tissue repair through timely modulation of the immune response.ABSTRACTMuscle injuries involve a complex inflammatory response in which macrophages are essential for ...
Raquel Lira Ortiz da Silva, Tainá Caroline dos Santos Malavazzi, Aline Souza Silva, Sandra Kalil Bussadori, Anna Carolina Ratto Tempestini Horliana, Fabio Daumas Nunes, Kristianne Porta Santos Fernandes, Maria Fernanda Setubal Destro Rodrigues, Raquel Agnelli Mesquita‐Ferrari   +8 more
wiley   +1 more source