Results 241 to 250 of about 57,341 (275)

Neutrophil Elastase and Neutrophil Extracellular Traps in the Tumor Microenvironment

2020
Tumor-associated neutrophils (TANs) play a major role during cancer development and progression in the tumor microenvironment. Neutrophil elastase (NE) is a serine protease normally expressed in neutrophil primary granules. Formation of neutrophil extracellular traps (NETs), a mechanism used by neutrophils, has been traditionally associated with the ...
Hai, Huang, Hongji, Zhang, Amblessed E, Onuma, Allan, Tsung   +3 more
openaire   +2 more sources

Antithrombin inactivation by neutrophil elastase requires heparin

The American Journal of Medicine, 1989
In certain thrombotic states, large declines in the levels of functional circulating antithrombin occur, which may reflect the highly active nature of the endothelial surface in suppressing excessive amounts of activated coagulation enzymes. Alternatively, we have recently observed an unexpected and paradoxical in vitro functioning of heparin that ...
R E, Jordan, R M, Nelson, J, Kilpatrick, J O, Newgren, P C, Esmon, M A, Fournel   +5 more
openaire   +2 more sources

Neutrophil Elastase

2008
Zhifu Sun, Ping Yang
openaire   +1 more source

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

Nature Communications, 2022
Elisabeth S Butz, Cheng-Chang Chen, Veronika Kudrina   +2 more
exaly  

Anti-protease Treatments Targeting Plasmin(ogen) and Neutrophil Elastase May Be Beneficial in Fighting COVID-19

Physiological Reviews, 2020
Alain R Thierry
exaly  

Neutrophil elastase: From mechanisms to therapeutic potential

Journal of Pharmaceutical Analysis, 2023

exaly  

A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy

Nature Communications, 2023
Xiaogang Qu
exaly  

Neutrophil Elastase Inhibitors

2001
Robin A. Smith, Robert A. Stockley, Simon T. Hodgson   +2 more
openaire   +1 more source

Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock

Biomaterials, 2020
Cameron M Louttit, James J Moon
exaly  

Serglycin in neutrophils: retention of neutrophil elastase in granules and inhibition of neutrophil elastase activity during storage

2011
The 2010 Biennial Meeting of the American Society for Matrix Biology (ASMB), Charleston, S.C., 24-27 October 2010.
Shum, DKY, Chan, SCH, Ip, SCH
openaire   +1 more source