Results 121 to 130 of about 14,012 (156)

Neutrophil gelatinase-associated lipocalin (NGAL): the clinician’s perspective

Clinical Chemistry and Laboratory Medicine, 2012
Introduction: Neutrophil gelatinase-associated lipocalin (NGAL), originally discovered in the leukocyte neutrophil and than extensively studied in renal tissues, is now under focus as a “ prognostic ” biomarker, potentially useful in risk stratifi cation of a variety of cardiovascular as well as neoplastic and infl ammatory conditions. The same journey
Salvatore Di Somma, Gianfranco Cervellin   +1 more
exaly   +3 more sources

Neutrophil gelatinase-associated lipocalin

Current Opinion in Critical Care, 2010
Acute kidney injury (AKI) is a major clinical problem in hospitalized patients. Effective treatment and early diagnosis of this syndrome are not currently available. This review focuses on recent studies examining the biological characteristics and the diagnostic and prognostic value of a novel biomarker--neutrophil gelatinase-associated lipocalin ...
Michael, Haase, Rinaldo, Bellomo, Anja, Haase-Fielitz   +2 more
openaire   +3 more sources

Neutrophil gelatinase associated lipocalin

The Scientific Journal of Al-Azhar Medical Faculty, Girls, 2017
Introduction Serum creatinine is a late marker of acute kidney injury (AKI) and its alterations are often not apparent until 48–72 h postinjury. Urine and plasma neutrophil gelatinase associated lipocalin (NGAL) measurements may represent early biomarker of AKI in intensive care, being able to predict this complication ∼2 days ...
Hoda M. El-Sayed, Hayam H. Mansour, Essam Abd El-Aziz Abd El-Mobdy, Ragaa R. Mohammed, Ahmed N. Ajam, Haytham S. Abd El-Hamid, Mohammed S. El-Din Zaky, Mohamed H. Biomy   +7 more
openaire   +1 more source

Neutrophil Gelatinase-Associated Lipocalin in Cancer

2014
Neutrophil gelatinase-associated lipocalin (NGAL), also known as lipocalin-2, is a 178-amino acid protein which exists in three molecular forms, including a 25-kDa monomer, a 45-kDa homodimer, and a 135-kDa heterodimer complexed with matrix metalloproteinase 9 (MMP-9).
LIPPI, Giuseppe, MESCHI, Tiziana, NOUVENNE, ANTONIO, Mattiuzzi, Camilla, BORGHI, Loris   +4 more
openaire   +4 more sources

Neutrophil Gelatinase-Associated Lipocalin in the Early Diagnosis of Peritonitis: The Case of Neutrophil Gelatinase-Associated Lipocalin

2012
Neutrophil gelatinase-associated lipocalin (NGAL), a protein involved in iron handling, has been recognized as a marker of inflammation. In this regard, serum and urine NGAL levels have proven a useful diagnostic tool for acute kidney injury. Bacterial peritonitis is an all too common complication of peritoneal dialysis (PD) and while diagnosis in most
Martino F. K., Filippi I., Giavarina D., Kaushik M., Rodighiero M. P., Crepaldi C., Teixeira C., Nadal A. F., Rosner M. H., Ronco C.   +9 more
openaire   +2 more sources

Removal of neutrophil gelatinase‐associated lipocalin by extracorporeal therapies

Hemodialysis International, 2010
AbstractNeutrophil gelatinase‐associated lipocalin (NGAL) protein is an early biomarker for acute kidney injury (AKI). It is unknown if extracorporeal therapies (EC) have an effect on circulating NGAL levels. This study was designed to describe the kinetics of NGAL molecule in different EC techniques and to evaluate NGAL clearance in different ...
Bobek I, Gong D, De Cal M, Cruz D, Chionh CY, Haapio M, Soni SS, Nalesso F, Lentini P, Garzotto F, Corradi V, Ronco C   +11 more
openaire   +2 more sources

Neutrophil Gelatinase-Associated Lipocalin

Blood purification, 2014
Acute kidney injury (AKI) remains a challenge in terms of diagnosis and classification, its morbidity and mortality remaining high in the face of improving clinical protocols. Current clinical criteria use serum creatinine (sCr) and urine output to classify patients.
Ronco, Claudio, Legrand, Matthieu, Goldstein, Stuart L., Hur, Mina, Nam Tran, [No Value], Howell, Eric C., Cantaluppi, Vincenzo, Cruz, Dinna N., Damman, Kevin, Bagshaw, Sean M., Di Somma, Salvatore, Lewington, Andrew   +11 more
openaire   +1 more source

Glycosylation of Natural Human Neutrophil Gelatinase B and Neutrophil Gelatinase B-Associated Lipocalin

Biochemistry, 1999
Gelatinase B is a matrix metalloproteinase (MMP-9) involved in tissue remodeling, development, cancer, and inflammation. Neutrophils produce three major forms of (pro)gelatinase B: 92 kDa monomers, homodimers, and complexes of gelatinase B covalently bound to neutrophil gelatinase B-associated lipocalin (NGAL).
Rudd, P., Mattu, T., Masure, S., Bratt, T., Van Den Steen, P., Wormald, M., Küster, B., Harvey, D., Borregaard, N., Van Damme, J., Dwek, R., Opdenakker, G.   +11 more
openaire   +3 more sources

Neutrophil gelatinase-associated lipocalin in kidney transplantation: A review

Transplantation Reviews, 2015
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed by kidney tubular cells in response to ischemia, but may also be an early indicator of immunological rejection, calcineurin inhibitor toxicity, obstructive nephropathy, subclinical tubulitis or infection.
Juan C, Ramirez-Sandoval, William, Herrington, Luis E, Morales-Buenrostro   +2 more
openaire   +2 more sources

Up-regulation of neutrophil gelatinase-associated lipocalin in cholesteatoma

Acta Oto-Laryngologica, 2009
Neutrophil gelatinase-associated lipocalin (NGAL) and Ki-67 expression were up-regulated in cholesteatoma and the expression pattern of NGAL in the epithelial layer was inversely related to the expression of Ki-67. Therefore, NGAL may be related to dysregulated differentiation in the keratinocytes during the development of a cholesteatoma.We ...
Hyun-Jae, Woo, Jun-Chul, Park, Chang Hoon, Bae, Si-Youn, Song, Heung-Man, Lee, Yong-Dae, Kim   +5 more
openaire   +2 more sources