Results 51 to 60 of about 749,501 (334)
Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis. [PDF]
, 2017 BACKGROUND: Central nervous system tuberculosis (CNS-TB) may be fatal even with treatment. Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is ...
Brilha, S +6 more
core +1 more source
Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP
Molecular Medicine, 2022 Background Neutrophils are the most abundant innate immune cells in the circulating blood, and they act as the first responder against bacterial and fungal infection. However, accumulation of activated neutrophils can cause severe inflammation and tissue
Satoshi Takizawa +4 more
doaj +1 more source
Nature Immunology, 2014 In this Review we discuss data demonstrating recently recognized aspects of neutrophil homeostasis in the steady state, granulopoiesis in 'emergency' conditions and interactions of neutrophils with the adaptive immune system. We explore in vivo observations of the recruitment of neutrophils from blood to tissues in models of blood-borne infections ...
Nauseef, William M, Borregaard, Niels
openaire +4 more sources
In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury [PDF]
, 2006 Background: Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS ...
McAuley, Daniel F. +4 more
core +2 more sources
Olfactomedin 4 marks a subset of neutrophils in mice
Innate Immunity, 2019 Neutrophils are the most abundant immune cell of the innate immune system and participate in essential immune functions. Heterogeneity within neutrophils has been documented, but it is difficult to distinguish if these are altered activation states of a ...
Matthew N Alder +5 more
doaj +1 more source
Mineral trioxide aggregate induces the release of matrix metalloproteinase-9 by human neutrophils
Journal of Dental Sciences, 2013 Background/purpose: As a pulp capping agent, mineral trioxide aggregate (MTA) is commonly applied on inflamed tissues that present with a variety of immunocompetent cells, including neutrophils. Neutrophils are a major source of matrix metalloproteinases
Ya-Yun Lee +5 more
doaj +1 more source
Laboratory Animal Research, 2021 Increases of neutrophils and osteoclasts are pathological changes of periodontitis. RANKL is an osteoclast differentiation factor. The effect of periodontopathogen LPS on RANKL-expressing neutrophils has not been clarified yet.
Ae Ri Kim +4 more
doaj +1 more source
Human CD79b+ neutrophils in the blood are associated with early-stage melanoma
Frontiers in Immunology, 2023 PurposeDue to their abundance in the blood, low RNA content, and short lifespan, neutrophils have been classically considered to be one homogenous pool.
Melissa A. Meyer +20 more
doaj +1 more source
Mycobacterium tuberculosis Drives Expansion of Low-Density Neutrophils Equipped With Regulatory Activities [PDF]
, 2019 In human tuberculosis (TB) neutrophils represent the most commonly infected phagocyte but their role in protection and pathology is highly contradictory.
La Manna, M. P. +8 more
core +1 more source
Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]
, 2016 Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim +4 more
core +2 more sources