Results 81 to 90 of about 32,351 (183)

Possible hepatotoxic consequence of nevirapine use in juvenile albino rats [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2017
Context: Nevirapine (NVP) is used in human immunodeficiency virus exposed neonates. This could present safety concern due to decreased liver metabolizing enzymes activity and renal clearance in neonates.
Elias Adikwu, Bonsome Bokolo
doaj  

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2494-2506, September 2025.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Assessing the Barriers to Universal Antiretroviral Treatment Access for HIV/AIDS in South Africa [PDF]

, 2004
Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer.
Walker, Mary Beth
core   +2 more sources

Abnormal coagulation profile in people living with HIV-AIDS on combined Antiretroviral Therapy: findings from a case-control study in the Ho municipality, Ghana

The Pan African Medical Journal, 2018
INTRODUCTION: Although combined Anti-Retroviral Therapy (cART) has improved the quality of life and survival in people living with HIV-AIDS (PLWHA), there have been reports of increased non-AIDS related co-morbidities such as coagulopathies.
Richard Kobina Dadzie Ephraim, James Elikem Ahadzie, Patrick Adu, Joseph Boachie, Hope Agbodzakey, Prince Adoba, Obed Cudjoe   +6 more
doaj   +1 more source

2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

Molecules, 2013
Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used against HIV-1. Currently, NVP is the most widely used anti-HIV drug in developing countries, both in combination therapy and to prevent mother-to-child transmission of HIV.
M. Matilde Marques, Frederick A. Beland, M. Conceição Oliveira, Benjamin Wolf, Alexandra M. M. Antunes   +4 more
doaj   +1 more source

Prevalence of Chronic Kidney Disease and Associated Factors Among Adult HIV/AIDS Patients on HAART in Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Chronic kidney disease related to human immunodeficiency virus infection has become a significant concern in sub‐Saharan Africa, primarily due to the high prevalence of the virus, along with delays in diagnosis and the initiation of highly active antiretroviral therapy.
Gada Diba, Ahmedmenewer Abdu, Ephrem Tefera Solomon, Winner Kucha   +3 more
wiley   +1 more source

Nevirapine induced toxic epidermal necrolysis and non-Hodgkin lymphoma in a Human Immunodeficiency Virus positive patient

Indian Dermatology Online Journal, 2014
Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) is one of the important components of highly active antiretroviral therapy. It is sometimes associated with life-threatening adverse reactions.
Leelavathy Budamakuntla, Eswari Loganathan, Shwetha Suryanarayan, Kumar Abhishek, Sacchidanand Sarvajnamurthy   +4 more
doaj   +1 more source

Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy. [PDF]

, 2015
The objective of this study is to assess whether pregnancy is associated with an increased risk of liver enzyme elevation (LEE) and severe LEE in HIV-positive women on antiretroviral therapy (ART)
Anderson, J, Hill, T, Huntington, S, Newell, ML, Pillay, D, Sabin, C, Taylor, GP, the UK Collaborative HIV Cohort (UK CHIC) Study, the UK, Ireland National Study of HIV in Pregnancy, Childhood (NSHPC),, Thorne, C, Tookey, PA   +9 more
core   +1 more source

Chemical and Toxicological Analysis of Antiretroviral Drugs

Разработка и регистрация лекарственных средств, 2019
Introduction. Human Immunodeficiency Virus (HIV) is one of the main socially significant infection all over the world. HIV-positive patients take medical care, including antiretroviral drugs (ARVs) pharmacotherapy.
T. N. Komarov, M. V. Belova, D. D. Stolyarova, I. E. Shohin, D. S. Bogdanova, O. A. Miskiv, Yu. V. Medvedev, I. M. Korenskaya   +7 more
doaj   +1 more source

A Retrospective Survey of HIV Drug Resistance Among Patients 1 Year After Initiation of Antiretroviral Therapy at 4 Clinics in Malawi [PDF]

, 2012
In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because of limited treatment options, population-level surveillance of acquired human immunodeficiency virus drug resistance (HIVDR) is critical to ensuring long-term ...
Anthony Harries, Barth, Ben Chilima, Bennett, Bennett, Bethany L. Hedt, Carol Porter, Coetzee, Diane E. Bennett, Eddie Limbambala, Erik Schouten, George Bello, Hedt, Hosseinipour, Joep J. van Oosterhout, Johannessen, John Aberle-Grasse, Jordan, Kamoto, Kamya, Kouanfack, Koyalta, Kundai Moyo, Liu, Maldonado, Marcelin, Marconi, Michael R. Jordan, Mina Hosseinipour, Ministry of Health, Moses Massaquoi, Nellie Wadonda-Kabondo, Nzeyimana, Oyugi, Pillay, Puthanakit, Ralf Weigel, Storn Kabuluzi, Sungkanuparph, Wallis, Yu   +40 more
core   +2 more sources