Results 201 to 210 of about 54,991 (287)

Psychiatric Morbidity Among Adolescents and Young Adults Who Contacted Specialised Gender Identity Services in Finland in 1996–2019: A Register Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To examine the prevalence of severe psychiatric morbidity among gender‐referred adolescents, focusing on gender differences and outcomes related to medical gender reassignment. Methods Finnish nationwide cohort of all under‐23‐year‐old gender‐referred individuals between 1996 and 2019 (n = 2 083) and 16 643 matched controls.
Sami‐Matti Ruuska, Katinka Tuisku, Timo Holttinen, Riittakerttu Kaltiala   +3 more
wiley   +1 more source

Health risk perception and behavioral decision-making among online-dating MSM in Shandong, China: perspectives on HIV and new psychoactive substances. [PDF]

BMC Public Health
Chen Y, Yu H, Zhu X, Li L, Wang L, Zhuoma Y, Zhang N, Wang G, Ma W, Liao M.   +9 more
europepmc   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Qualitative and quantitative in silico toxicity profiling of "angel dust": phencyclidine (PCP) analogues as new psychoactive substances (3-HO-PCP, 3-MeO-PCP, 4-MeO-PCP, 3-HO-PCE, 3-MeO-PCE, 4-MeO-PCE). [PDF]

Arch Toxicol
Noga M, Jurowski K.
europepmc   +1 more source

Motives for New Psychoactive Substances Consumption among Young Adults in Uzbekistan: A Qualitative Study Protocol. [PDF]

Consort Psychiatr
Zakhidova G, Pikirenia U, Syunyakov T, Prilutskaya M.   +3 more
europepmc   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

New Psychoactive Substances Toxicity: A Systematic Review of Acute and Chronic Psychiatric Effects. [PDF]

Int J Mol Sci
Taflaj B, La Maida N, Tittarelli R, Di Trana A, D'Acquarica I.   +4 more
europepmc   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine-Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms. [PDF]

Adv Sci (Weinh)
Li Y, Li H, Wang H, Wang X.
europepmc   +1 more source