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Bioanalytical Methods for New Psychoactive Substances
2018Bioanalysis of new psychoactive substances (NPS) is very challenging due to the growing number of compounds with new chemical structures found on the drugs of abuse market. Screening, identification, and quantification in biosamples are needed in clinical and forensic toxicology settings, and these procedures are more challenging than the analysis of ...
Lea, Wagmann, Hans H, Maurer
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The Toxicology of New Psychoactive Substances
Therapeutic Drug Monitoring, 2016New psychoactive substances (NPSs) are substitutes for classical drugs of abuse and there are now compounds available from all groups of classical drugs of abuse. During 2014, the number of synthetic cathinones increased dramatically and, together with phenylethylamines, they dominate the NPS markets in the European Union. In total, 31 cathinones and 9
Elli, Tyrkkö +2 more
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Phencyclidine-Based New Psychoactive Substances
2018The serendipitous discovery of phencyclidine (PCP) in 1956 sets the stage for significant research efforts that resulted in a plethora of analogs and derivatives designed to explore the biological effects of this class. PCP soon became the prototypical dissociative agent that eventually sneaked through the doors of clinical laboratories and became an ...
Jason, Wallach, Simon D, Brandt
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Stimulant New Psychoactive Substances
Abstract Given the large numbers of stimulant NPS having recently been identified from web crawler activities, this chapter comments on the pharmacological, clinical pharmacological, toxicity, and acute/chronic treatment/management issues pertaining to a range of novel stimulants, including psychedelic phenethylamines, novel ...Fabrizio Schifano +7 more
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Fatal Poisonings Associated with New Psychoactive Substances
2018This chapter describes how new psychoactive substances (NPS) have been involved in fatal intoxications from 2010 and onwards. It summarizes the circumstances, antemortem symptoms, and adverse effects that have led to death after ingestion of one or more NPS and tabulates concentrations, and postmortem findings from these intoxications.Consumption of ...
Robert, Kronstrand +4 more
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New Psychoactive Substances (NPS)
2019วารสารสมาคมแพทย์นิติเวชแห่งประเทศไทย, 13, 2, 29 ...
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Mephedrone and New Psychoactive Substances
2016In the context of use and misuse of drugs and forensic toxicology, new psychoactive substances have arguably had more impact on toxicology than anything in the last five decades. This chapter describes the background to these substances, along with the analytical considerations.
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