Results 41 to 50 of about 592,747 (102)

Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1-deficient collie dogs. [PDF]

J Vet Pharmacol Ther, 2022
Abstract Afoxolaner, an insecticide and acaricide compound of the isoxazoline class, is available for dogs as an oral ectoparasiticide medicine (NexGard®) and as an oral endectoparasiticide medicine in combination with milbemycin oxime (MO), a macrocyclic lactone (NexGard® Spectra).
Drag M, Tielemans E, Mitchell E.
europepmc   +2 more sources

Efficacy of combination products containing sarolaner, moxidectin and pyrantel (Simparica Trio™) or afoxolaner and milbemycin (NexGard Spectra®) against induced infestations of Ixodes holocyclus in dogs

Parasites & Vectors, 2020
Background The Australian paralysis tick, Ixodes holocyclus, causes tick paralysis in dogs and cats in the eastern coastal regions of Australia. Prevention is the best option to protect dogs against this potentially fatal disease and sarolaner provides ...
Raj Packianathan, Andrew Hodge, Natalie Bruellke, Chrissie Jackson, Steven Maeder   +4 more
doaj   +1 more source

Unambiguous identification of Ancylostoma caninum and Uncinaria stenocephala in Australian and New Zealand dogs from faecal samples

Australian Veterinary Journal, Volume 101, Issue 10, Page 373-376, October 2023., 2023
Hookworms (Ancylostomatidae) are well‐known parasites in dogs due to their health impacts and zoonotic potential. While faecal analysis is the traditional method for detection, improvements in husbandry and deworming have decreased their prevalence in urban owned dogs.
T Stocker, I Scott, J Šlapeta
wiley   +1 more source

Reduced incidence of tick paralysis cases in dogs and cats at two emergency clinics in South‐East Queensland since 2015: new generation prophylactics as possible explanatory variables

Australian Veterinary Journal, Volume 101, Issue 9, Page 356-365, September 2023., 2023
Introduction This study aimed to determine the incidence of canine and feline tick paralysis cases presenting to two veterinary emergency hospitals before and after the introduction of new generation prophylactic acaricides. Methods This was a retrospective study, investigating the number of tick paralysis cases presenting to two emergency and critical
EM Ireland, J Heller, EM Leister, AM Padula   +3 more
wiley   +1 more source

SDR9C7 missense variant in a Chihuahua with non‐epidermolytic ichthyosis

Animal Genetics, Volume 54, Issue 4, Page 562-565, August 2023., 2023
Abstract Ichthyoses represent a heterogeneous group of cornification disorders that are associated with skin barrier defects. We investigated a 9‐month‐old Chihuahua showing excessive scale formation. Clinical and histopathological examinations revealed non‐epidermolytic ichthyosis and a genetic defect was suspected.
Sarah Kiener, Eloy Castilla, Vidhya Jagannathan, Monika Welle, Tosso Leeb   +4 more
wiley   +1 more source

Brucella suis in three dogs: presentation, diagnosis and clinical management

Australian Veterinary Journal, Volume 101, Issue 4, Page 133-141, April 2023., 2023
Brucella suis is an emerging, zoonotic disease predominantly affecting dogs and humans that engage in feral pig hunting in Australia and other countries. Although B. suis infection in dogs shares some clinical similarities to the host‐adapted species (B. canis), B.
CC Kneipp, AM Rose, J Robson, R Malik, AT Deutscher, AK Wiethoelter, SM Mor   +6 more
wiley   +1 more source

Insecticidal efficacy of afoxolaner against Stomoxys calcitrans (Diptera: Muscidae) in dogs

Current Research in Parasitology and Vector-Borne Diseases, 2021
The insecticidal activity of oral afoxolaner (NexGard®) against stable flies Stomoxys calcitrans (Diptera: Muscidae) that had fed on dogs was evaluated in a blinded, randomised, and negative controlled efficacy study.
Eric Tielemans, Nesrine Aouiche, Adriaan Saunders, J.F. Besselaar, Frédéric Beugnet   +4 more
doaj   +1 more source

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

Journal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 1-16, January 2023., 2023
Abstract In 2001 the molecular genetic basis of so‐called “ivermectin sensitivity” in herding breed dogs was determined to be a P‐glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called “the MDR1 mutation.” We have learned a great deal about P‐glycoprotein's role in drug disposition since that discovery, namely that P ...
Katrina L. Mealey, Jane G. Owens, Elaine Freeman   +2 more
wiley   +1 more source

Target animal safety evaluation of a novel topical combination of esafoxolaner, eprinomectin and praziquantel for cats

Parasite, 2021
The safety profile of NexGard® Combo, a novel topical product for cats combining esafoxolaner, eprinomectin and praziquantel, for the treatment and prevention of internal and external parasites, was evaluated in kittens, in two margin-of-safety studies ...
Gupta Aradhana, Baker Christine, Wang Hailun, Targa Norba, Pfefferkorn Anthony, Tielemans Eric   +5 more
doaj   +1 more source

Liver and spleen of hosts of Rhipicephalus linnaei exposed to synthetic (afoxolaner) and natural acaricides (esters from castor oil). A comparative clinical-morphological study [PDF]

Revista Brasileira de Parasitologia Veterinária, 2023
In dogs, Rhipicephalus linnaei transmits pathogens such as Ehrlichia canis, Babesia vogeli, and Hepatozoon canis. The veterinary market has synthetic acaricides to ticks control. Esters derived from castor oil are efficient.
Luís Fernando Sodelli, Odaiza da Silva, Bruna Jéssyca Nascimento Araújo, Maria Izabel Camargo-Mathias   +3 more
doaj   +1 more source