Results 61 to 70 of about 592,747 (102)

Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration

Veterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos, Tássia Ferreira, Fernanda Borek, Domenico Santoro, Lluis Ferrer, Marconi Farias   +5 more
wiley   +1 more source

Comparative efficacy of oral administrated afoxolaner (NexGard™) and fluralaner (Bravecto™) with topically applied permethrin/imidacloprid (Advantix®) against transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs [PDF]

, 2016
BACKGROUND : The ability of the topical spot-on Advantix® (50 % permethrin/10 % imidacloprid) to prevent transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs has previously been reported.
Erasmus, Heidi, Fourie, Josephus J., Josephus J. Fourie, Heidi Erasmus, Jongejan, Frans, Bettina Schunack, Dionne Crafford, Frans Jongejan, Crafford, Dionne, Schunack, Bettina   +9 more
core   +1 more source

Pharmacokinetics of Milbemycin Oxime in Pekingese Dogs after Single Oral and Intravenous Administration

Veterinary Medicine and Science, Volume 11, Issue 2, March 2025.
This study evaluates the pharmacokinetics of milbemycin oxime in Pekingese dogs after oral (tablet and nanoemulsion) and intravenous administration. The nanoemulsion showed faster absorption, higher peak concentration, and near‐complete bioavailability (99.26%) compared to tablets (51.44%), suggesting its potential as a superior alternative for ...
Ze‐En Li, Ming‐Hui Duan, Yan Dai, Yang‐Guang Jin, Yue Liu, Yan‐Ni Zhang, Xing‐Ping Li, Fan Yang   +7 more
wiley   +1 more source

Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Amblyomma americanum in cats

Parasite, 2021
Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel in NexGard® Combo, a novel topical endectoparasiticide product for cats.
Prullage Joe, Baker Christine, Mansour Abdelmoneim, McCall Scott, Young David, Tielemans Eric   +5 more
doaj   +1 more source

Efficacy of a chewable tablet containing sarolaner, moxidectin and pyrantel for the treatment of generalised demodicosis in dogs

Veterinary Dermatology, Volume 36, Issue 1, Page 34-42, February 2025.
Background – Demodicosis is common in dogs and is caused by proliferation of commensal Demodex canis mites. Objective – To evaluate the efficacy of sarolaner in combination with moxidectin and pyrantel (SMP) for the treatment of generalised demodicosis in dogs.
Csilla Becskei, Julian Liebenberg, Tiago Fernandes, Stasia Borowski, Lina D'Hanis, Sean P. Mahabir   +5 more
wiley   +1 more source

Assessment of the insecticidal activity of oral afoxolaner against Phlebotomus perniciosus in dogs

Parasite, 2019
Twelve healthy dogs were included in this laboratory efficacy study. Six dogs were randomly allocated based on body weight to an untreated control group and six to an afoxolaner (NexGard®) treated group.
Perier Nadège, Lebon Wilfried, Meyer Leon, Lekouch Noua, Aouiche Nesrine, Beugnet Frédéric   +5 more
doaj   +1 more source

Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Echinococcus multilocularis infections in cats

Parasite, 2021
NexGard® Combo, a novel topical endectoparasiticide formulation for cats combining esafoxolaner, eprinomectin and praziquantel, for the treatment of internal and external parasite infestations, including arthropods, nematodes and cestodes, was tested for
Prullage Joe, Bowman Dwight, Ulrich Michael, Tielemans Eric   +3 more
doaj   +1 more source

Consequences of repeated sarcoptic mange outbreaks in an endangered mammal population

Ecography, Volume 2024, Issue 10, October 2024.
Diseases and parasites are important drivers of population dynamics in wild mammal populations. Small and endangered populations that overlap with larger, reservoir populations are particularly vulnerable to diseases and parasites, especially in ecosystems highly influenced by climate change.
Johan Wallén, Rasmus Erlandsson, Malin Larm, Tomas Meijer, Karin Norén, Anders Angerbjörn   +5 more
wiley   +1 more source

Effective treatment with afoxolaner (NexGard) of Trixacarus caviae in a pet guinea pig

Veterinary Medicine and Science, Volume 10, Issue 5, September 2024.
One female guinea pig was presented with dermatological problems and was confirmed to be infested by Trixacarus caviae mites. The animal was treated with a single oral dose of 2.50 mg/kg afoxolaner, with the complete remission of clinical signs and no mites at the microscopic examination after 4 weeks.
Georgiana Deak, Miruna‐Maria Matei, Anca‐Alexandra Doboși, Aura Livia Ursache, Andrada Negoescu, Marian Taulescu   +5 more
wiley   +1 more source

Detection of Anaplasma phagocytophilum in an inflammatory pericardial effusion of a dog

Journal of Veterinary Internal Medicine, Volume 38, Issue 4, Page 2339-2343, July/August 2024.
Abstract An 11‐year‐old female spayed German Wirehaired Pointer with a 1‐week history of lethargy, hyporexia, diarrhea, and coughing presented with pericardial effusion causing cardiac tamponade. An echocardiogram revealed no structural cause for pericardial effusion.
Betsy K. Murdock, Jonathan F. Bach, Barbara A. Qurollo, Erin W. Lashnits, Kristen R. Friedrichs   +4 more
wiley   +1 more source